文献类型： 外文期刊
第一作者： Yue, Shousong
作者： Yue, Shousong;Picimbon, Jean-Francois;He, Qiuxia;Picimbon, Jean-Francois;Picimbon, Jean-Francois
作者机构： Shandong Acad Agr Sci, Biotechnol Res Ctr, 202 Gongye North Rd, Jinan 250100, Shandong, Peoples R China;Shandong Acad Sci, Sci & Technol Serv Platform Shandong Acad Sci, Foreign Students Pioneer Pk, Jinan 250103, Shandong, Peoples R China;Qilu Univ Technol, Sch Bioengn, 3501 Univ Rd, Jinan 250353, Shandong, Peoples R China
关键词： CSP model; Cell ribosome; Glycine insertion; Cysteine insertion; Protein recoding; Cell multifunction; Mutational alteration; Genetic disease; Malignant tumor; CUP
期刊名称：CLINICAL & TRANSLATIONAL ONCOLOGY （ 2022影响因子：3.4； 五年影响因子：3.1 ）
ISSN： 1699-048X
年卷期： 2023 年 25 卷 6 期
收录情况： SCI
摘要： This study reviews newly discovered insect peptide point mutations as new possible cancer research targets. To interpret newly discovered peptide point mutations in insects as new possible cancer research targets, we focused on the numerous peptide changes found in the 'CSP' family on the sex pheromone gland of the female silkworm moth Bombyx mori. We predict that the Bombyx peptide modifications will have a significant effect on cancer CUP (cancers of unknown primary) therapy and that bacterial peptide editing techniques, specifically Lactobacillus combined to CRISPR, will be used to regulate ribosomes and treat cancer in humans.
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