文献类型： 外文期刊
第一作者： Sun, Jing
作者： Sun, Jing;Ma, Jiale;Li, Manman;Wang, Rongye;Liang, Naiyun;Zhao, Yunfang;Zheng, Jiao;Song, Yuelin;Tu, Pengfei;Huo, Huixia;Li, Jun;Sun, Jing
作者机构：
关键词： Verbenaceae; Vitex negundo var. cannabifolia; Iridoid glucoside; Stomachache; Human gastric epithelial cells
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.873； 五年影响因子：1.875 ）
ISSN： 1874-3900
年卷期： 2022 年 47 卷
页码：
收录情况： SCI
摘要： Five new iridoid glucosides, cannabifolisides A-E (1 - 5), together with nine analogues (6 - 14), were isolated from the leaves of Vitex negundo var. cannabifolia. Their structures were elucidated by spectroscopic data (NMR, UV, IR, and MS) analyses and comparison of their spectroscopic and physical data with the literature values. The protective effect of isolated compounds on human gastric epithelial cells were evaluated by measuring the enhanced cell viability of GES-1 cell insulted by TCA. Among these, compounds 4, 6, 8, 10, 12, and 14 remarkably increased the cell viability in a concentration-depend manner.
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