Haplotype diversity in MC1R locus between the Min and white-haired pig breeds

文献类型： 外文期刊

第一作者： Lu, C.

作者： Lu, C.;Yu, H.;Xing, Y.;Cheng, Y. -Y.;Wu, Q. -Y.;Li, S. -M.;Fu, H. -Y.;Zhang, X.;Hao, L. -L.;Liu, D.

作者机构：

关键词： Min pig; MC1R; linkage disequilibrium; haplotype; phylogenetic analysis

期刊名称：ACTA AGRICULTURAE SCANDINAVICA SECTION A-ANIMAL SCIENCE （ 影响因子：0.684； ）

ISSN： 0906-4702

年卷期： 2017 年 67 卷 1-2 期

页码：

收录情况： SCI

摘要： In this article, we investigated the genetic variations in the coding region of porcine melanocortin receptor 1 (MC1R) gene in three pig breeds (Min, Yorkshire and Landrace) with black and white coat colors. Six polymorphic sites were found to be significantly associated with coat color. Two blocks were identified in the linkage disequilibrium map, the haplotypes in the first block are nt67/68indelCC and nt67/68indel--, and the haplotypes in the second block are ACCGA and GTTAG. The median-joining network diagram of MC1R haplotypes showed most Min pigs and other Asia domestic breeds own similar haplotypes to ACCGA, while the haplotypes of Europe pig breeds are similar to GTTAG. The phylogenetic analysis of the MC1R CDS further showed Min pigs are close to Laiwu pigs (Shandong, China), which indicated that the black coat color trait of Min pig might be originated and evolved from the black pig breed in Shandong Peninsula of China.

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