Effects of Bupleurum extract on blood metabolism, antioxidant status and immune function in heat-stressed dairy cows

文献类型： 外文期刊

第一作者： Cheng Jian-bo

作者： Cheng Jian-bo;Fan Cai-yun;Sun Xian-zhi;Wang Jia-qi;Zheng Nan;Wang Jia-qi;Zheng Nan;Zhang Xing-kai;Qin Jun-jie;Wang Xiu-min

作者机构：

关键词： Bupleurum extract; blood metabolites; heat stress; dairy cows

期刊名称：JOURNAL OF INTEGRATIVE AGRICULTURE （ 影响因子：2.848； 五年影响因子：2.979 ）

ISSN： 2095-3119

年卷期： 2018 年 17 卷 3 期

页码：

收录情况： SCI

摘要： This experiment was conducted to evaluate the effects of Bupleurum extract (BE) on blood metabolites, antioxidant status, and immune function in dairy cows under heat stress. Forty lactating Holstein cows were randomly assigned to 1 of 4 treatments. The treatments consisted of 0, 0.25, 0.5, and 1.0 g of BE kg(-1) dry matter. Supplementation with BE decreased (P<0.05) blood urea nitrogen (BUN) contents and increased blood total protein (TP) and albumin (ALB) levels compared with control cows, but it had no effects (P>0.05) on blood glucose (GLU), nonesterified fatty acid (NEFA), total triglyceride (TG), low-density lipoprotein cholesterol (LDL-C), and high density lipoprotein cholesterol (HDL-C). Compared with control cows, cows fed BE had higher (P<0.05) superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) activity. However, supplementation with BE had no effect (P>0.05) on total antioxidant capacity (T-AOC) or malondialdehyde (MDA) levels. The immunoglobulin (Ig) A and G contents increased (P<0.05) in cows fed 0.25 or 0.5 g of BE kg(-1). Interleukin (IL)-2 and IL-4 levels were higher (P<0.05) in cows fed 0.5 and 1.0 g of BE kg(-1), and IL-6 was significantly elevated (P<0.05) in cows fed 0.5 g of BE kg(-1). There were no treatment effects (P>0.05) on the CD4(+) and CD8(+) T lymphocyte ratios, CD4(+)/CD8(+) ratio, or tumor necrosis factor-alpha (TNF-alpha) level among the groups. These findings suggest that BE supplementation may improve protein metabolism, in addition to enhancing antioxidant activity and immune function in heat-stressed dairy cows.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序