An NBD-NH2 fluorescent probe for bioimaging: existence of a specific detection of ClO-
文献类型: 外文期刊
第一作者: Yang, Yunxia
作者: Yang, Yunxia;Xu, Mengsheng;Wang, Jianhong;Chen, Jipeng;Wang, Le;Zhang, Di
作者机构:
关键词: NBD-NH2; Fluorescent probe; Hypochlorous
期刊名称:MONATSHEFTE FUR CHEMIE ( 影响因子:1.451; 五年影响因子:1.519 )
ISSN: 0026-9247
年卷期: 2018 年 149 卷 6 期
页码:
收录情况: SCI
摘要: A fluorescent probe 4-amino-7-nitrobenz-2-oxa-1,3-diazole NBD-NH2 for critical sensing hypochlorous (ClO-) has been developed in this paper. Probe NBD-NH2 exhibited excellent sensitivity and high selectivity toward detection of ClO- in CH3CH2OH/HEPES solution (1:4, v/v, 10 mM, pH 7.4), where the detection limit as low as 40 nM. The green fluorescence of NBD-NH2 was distinctly quenched by addition of ClO-. In addition, the new probe was also applied for bioimaging using HeLa cells and exist a critical detection of ClO- in living cells. [GRAPHICS] .
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