Roles of Probiotic Lactobacilli Inclusion in Helping Piglets Establish Healthy Intestinal Inter-environment for Pathogen Defense

文献类型： 外文期刊

第一作者： Yang, Jiajun

作者： Yang, Jiajun;Qian, Kun;Wang, Chonglong;Wu, Yijing

作者机构：

关键词： Lactobacillus; Microbiome; Piglets; Pathogen; Defense

期刊名称：PROBIOTICS AND ANTIMICROBIAL PROTEINS （ 影响因子：4.609； 五年影响因子：4.585 ）

ISSN： 1867-1306

年卷期： 2018 年 10 卷 2 期

页码：

收录情况： SCI

摘要： The gastrointestinal tract of pigs is densely populated with microorganisms that closely interact with the host and with ingested feed. Gut microbiota benefits the host by providing nutrients from dietary substrates and modulating the development and function of the digestive and immune systems. An optimized gastrointestinal microbiome is crucial for pigs' health, and establishment of the microbiome in piglets is especially important for growth and disease resistance. However, the microbiome in the gastrointestinal tract of piglets is immature and easily influenced by the environment. Supplementing the microbiome of piglets with probiotic bacteria such as Lactobacillus could help create an optimized microbiome by improving the abundance and number of lactobacilli and other indigenous probiotic bacteria. Dominant indigenous probiotic bacteria could improve piglets' growth and immunity through certain cascade signal transduction pathways. The piglet body provides a permissive habitat and nutrients for bacterial colonization and growth. In return, probiotic bacteria produce prebiotics such as short-chain fatty acids and bacteriocins that benefit piglets by enhancing their growth and reducing their risk of enteric infection by pathogens. A comprehensive understanding of the interactions between piglets and members of their gut microbiota will help develop new dietary interventions that can enhance piglets' growth, protect piglets from enteric diseases caused by pathogenic bacteria, and maximize host feed utilization.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序