Molecular characterisation of the buffalo SCAP gene and its association with milk production traits in water buffaloes

文献类型： 外文期刊

第一作者： Deng, Tingxian

作者： Deng, Tingxian;Ma, Xiaoya;Pang, Chunying;Liang, Shasha;Lu, Xingrong;Duan, Anqin;Liang, Xianwei

作者机构：

关键词： Buffalo; milk production traits; SCAP; single nucleotide polymorphism

期刊名称：JOURNAL OF DAIRY RESEARCH （ 影响因子：1.904； 五年影响因子：2.019 ）

ISSN： 0022-0299

年卷期： 2018 年 85 卷 2 期

页码：

收录情况： SCI

摘要： The study reported in this Research Communication was conducted to investigate the molecular characterisation of buffalo SCAP gene, expression analysis, and the association between single nucleotide polymorphisms and milk production traits in 384 buffaloes. Sequence analysis revealed the SCAP gene had an open reading frame of 3837 bp encoding 1279 amino acids. A ubiquitous expression profile of SCAP gene was detected in various tissues with extreme predominance in the mammary gland during early lactation. Moreover, eleven SNPs in buffalo SCAP gene were identified, six of them (g.1717600A>G, g.1757922C>T, g.1758953G>A, g.1759142C>T, g.1760740G>A, and g.1766036T>C) were found to be significantly associated with 305-day milk yield. Thus, buffalo SCAP could sever as a candidate gene affecting milk production traits in buffalo and the identified SNPs might potentially be genetic markers.

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