An enhanced sensitivity and cleanup strategy for the nontargeted screening and targeted determination of pesticides in tea using modified dispersive solid-phase extraction and cold-induced acetonitrile aqueous two-phase systems coupled with liquid chromatography-high resolution mass spectrometry

文献类型： 外文期刊

第一作者： Wang, Feiquan

作者： Wang, Feiquan;Xiao, Bin;Wang, Feiquan;Li, Shaohua;Feng, Hua;Yang, Yajun;Chen, Dawei

作者机构：

关键词： Pesticides; Tea; Matrix effect; Dispersive solid-phase extraction; Aqueous two-phase systems; High resolution mass spectrometry

期刊名称：FOOD CHEMISTRY （ 影响因子：7.514； 五年影响因子：7.516 ）

ISSN： 0308-8146

年卷期： 2019 年 275 卷

页码：

收录情况： SCI

摘要： At present, matrix interferences in tea are still a great challenge for analysis of multi-pesticide residues. Herein, a simple sample preparation method was developed based on the modified dispersive solid-phase extraction (DSPE) procedure and cold-induced acetonitrile aqueous two-phase systems (ATPS). In modified DSPE procedure, polyvinylpolypyrrolidone (PVPP) was selected as the matrix dispersive adsorbent to remove polyphenols from the tea with the removal rate of > 98.3%. Using cold-induced acetonitrile ATPS, caffeine of the tea extract was sharply reduced by 81.2%, and a 0.798-3.167 of enrichment factor for the representative pesticides was achieved. In liquid chromatography-high resolution mass spectrometry analysis, a full scan/data independent acquisition approach was used for the nontargeted screening and targeted determination of pesticides. In data analysis, an in-house database of pesticides was constructed, and a simple accurate mass calibration method was used to correct the accurate mass variation, which was conducive to reduce the number of false detects.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序