Interaction between Gemini Dodecyl O-Glucosides-Based Multilayer Vesicles and beta-Lactoglobulin: The Dominant Role of Surface Charge

文献类型： 外文期刊

第一作者： Feng, Jin

作者： Feng, Jin;Xu, Lujing;Liu, Songbai;Feng, Jin;Wang, Hua

作者机构：

关键词： multilayer niosomal vesicles; BLG-vesicle interaction; steady-state fluorescence; isothermal titration calorimetry; protein precipitation

期刊名称：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY （ 影响因子：5.279； 五年影响因子：5.269 ）

ISSN： 0021-8561

年卷期： 2019 年 67 卷 3 期

页码：

收录情况： SCI

摘要： Novel Gemini dodecyl O-glucoside-based primary, secondary, and tertiary vesicles were developed in this work utilizing layer-by-layer deposition of polysaccharides (e.g., sodium carboxymethyl cellulose and chitosan), and their interaction with beta-lactoglobulin (BLG) was carefully investigated. The increase of polysaccharide layers on primary vesicles led to a monotonic increase in size and consecutive reversal of surface charge. Polysaccharide deposition significantly retarded the vesicle aggregation and degradation of entrapped catechin laurate during storage. Steady-state fluorescence, isothermal titration calorimetry, and protein precipitation analyses revealed the surface charge dependence of the interactions between vesicles and a model milk protein BLG, which were much stronger when they were charged oppositely than when they presented the same type of surface charge. It was highlighted that the surface charge of vesicles could be tuned by differently charged coatings to accommodate to that of the milk proteins in the food matrix. This work will contribute to the practical application of niosomal vesicles loaded with bioactive compounds to fortify dairy products.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序