A phytochemical investigation of Stemona parviflora roots reveals several compounds with nematocidal activity

文献类型： 外文期刊

第一作者： Huang, Sheng-Zhuo

作者： Huang, Sheng-Zhuo;Kong, Fan-Dong;Zhou, Li-Man;Ma, Qing-Yun;Wang, Qi;Mei, Wen-Li;Dai, Hao-Fu;Zhao, You-Xing;Chen, Gao;Cai, Xiang-Hai

作者机构：

关键词： Stemona parviflora; Stemonaceae; Phenanthrene; Stilbene; Nematocidal activity

期刊名称：PHYTOCHEMISTRY （ 影响因子：4.072； 五年影响因子：4.132 ）

ISSN： 0031-9422

年卷期： 2019 年 159 卷

页码：

收录情况： SCI

摘要： Twelve undescribed compounds including six phenanthrene derivatives (parviphenanthrines A-F), two stilbene derivatives (parvistilbines A-B), three esters (parviesters A-C), and one sesquiterpenoid (parvidiol A) were isolated from the roots of Stemona parviflora, together with twenty-two known ones. The structures of the undescribed compounds were elucidated based on the analyses of their spectroscopic data. The absolute configuration of parviphenanthrine A was determined by the quantum ECD calculations. Parviphenanthrines A and E, stemanthrene A, stilbostenin E, 4-hydroxy-benzenepropanol-alpha-benzoate, and (E)-4-hydroxycinnamic acid methyl ester showed nematocidal activity against Meloidogyne incognita with IC50 values of 14.02 +/- 0.32, 2.51 +/- 0.13, 17.10 +/- 0.65, 2.05 +/- 0.07, 4.22 +/- 0.31, and 1.07 +/- 0.05 mu m, respectively.

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