The Glucose-Lowering Effect of Foxtail Millet in Subjects with Impaired Glucose Tolerance: A Self-Controlled Clinical Trial

文献类型： 外文期刊

第一作者： Ren, Xin

作者： Ren, Xin;Zhang, Min;Ren, Xin;Yin, Ruiyang;Hou, Dianzhi;Xue, Yong;Wu, Jihong;Hu, Jinrong;Hu, Xiaosong;Shen, Qun;Diao, Xianmin;Zhang, Yumei

作者机构：

关键词： dietary intervention; whole foxtail millet; blood glucose; impaired glucose tolerance

期刊名称：NUTRIENTS （ 影响因子：5.717； 五年影响因子：6.349 ）

ISSN： 2072-6643

年卷期： 2018 年 10 卷 10 期

页码：

收录情况： SCI

摘要： Foxtail millet has relatively low starch digestibility and moderate glycemic index compared to other grains. Since there are still no clinical researches regarding its long-term effect on blood glucose, this self-controlled study was conducted to investigate the glucose-lowering effect of foxtail millet in free-living subjects with impaired glucose tolerance (IGT). Fifty g/day of foxtail millet was provided to enrolled subjects throughout 12 weeks and the related clinical parameters were investigated at week 0, 6 and 12, respectively. After 12 weeks of foxtail millet intervention, the mean fasting blood glucose of the subjects decreased from 5.7 +/- 0.9 mmol/L to 5.3 +/- 0.7 mmol/L (p < 0.001) and the mean 2 h-glucose decreased from 10.2 +/- 2.6 mmol/L to 9.4 +/- 2.3 mmol/L (p = 0.003). The intake of foxtail millet caused a significant increase of serum leptin (p = 0.012), decrease of insulin resistance (p = 0.007), and marginal reduction of inflammation. Furthermore, a sex-dependent difference in glucose-lowering effect of foxtail millet was observed in this study. Foxtail millet could improve the glycemic control in free-living subjects with IGT, suggesting that increasing the consumption of foxtail millet might be beneficial to individuals suffering from type 2 diabetes mellitus.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序