文献类型： 外文期刊

第一作者： Guan, Mei Yan

作者： Guan, Mei Yan;Zhu, Ya Xin;Liu, Xing Xing;Jin, Chong Wei;Guan, Mei Yan

作者机构：

关键词： Cadmium; S-nitrosoglutathione reductase; IRON-REGULATED TRANSPORTER 1; Cadmium uptake; Arabidopsis

期刊名称：PLANT AND SOIL （ 影响因子：4.192； 五年影响因子：4.712 ）

ISSN： 0032-079X

年卷期： 2019 年 438 卷 1-2 期

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收录情况： SCI

摘要： Background and aimsIncreasing cadmium (Cd) contamination of agricultural soils is a serious problem. Identification of the mechanisms that control Cd uptake by roots is essential if we wish to improve the efficiency of plants in removing Cd from contaminated soils.MethodsWe dissected the role and the mechanism of S-nitrosoglutathione reductase (GSNOR) in regulating root Cd uptake in Arabidopsis plants using GSNOR-related mutants and pharmacological methods.ResultsExposure to Cd stimulated the activity of GSNOR in roots. Both treatment with S-nitrosoglutathione (substrate of GSNOR) in wild-type plants and loss of GSNOR function in gsnor mutants improved expression of IRON-REGULATED TRANSPORTER 1 (IRT1) and increased root Cd uptake, thereby elevating the Cd levels in plants. The opposite patterns were observed in the GSNOR over-expression transgenic plant GSNOR(OE), suggesting a negative regulation of IRT1 expression and Cd uptake by GSNOR. However, both the improvement of Cd uptake owing to S-nitrosoglutathione treatment or GSNOR mutation and the inhibition of Cd uptake due to GSNOR over-expression, could be blocked by loss of function of IRT1 in plants.ConclusionsWe concluded that induction of GSNOR reduced Cd uptake because of its negative regulation of IRT1 in roots, which lowered Cd accumulation in plants.

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