Trans-organ analysis of gene co-expression networks reveals a mobile long-distance regulator that balances shoot and root development in Arabidopsis

文献类型： 外文期刊

第一作者： Ye, Jia Yuan

作者： Ye, Jia Yuan;Jin, Chong Wei;Zheng, Shao Jian;Ye, Jia Yuan;Sakuraba, Yasuhito;Zhuo, Meng Na;Torii, Yousuke;Ohtsuki, Namie;Yanagisawa, Shuichi;Tian, Wen Hao;Mochida, Keiichi

作者机构：

期刊名称：NATURE PLANTS （ 影响因子：13.6； 五年影响因子：17.0 ）

ISSN： 2055-026X

年卷期： 2025 年 11 卷 8 期

页码：

收录情况： SCI

摘要： Long-distance regulation between individual organs is a fundamental process for the optimized adaptation of the plant body to diverse environments. However, systematic methods for identifying key genes for long-distance regulation are currently unavailable. Here we present a new approach, trans-organ analysis of gene co-expression networks, which offers a unique way of identifying candidates for such genes. This approach revealed that TGA7 functions as a shoot-to-root mobile bZIP transcription factor in Arabidopsis to activate photosynthetic genes directly in shoots and nitrate-uptake-related genes, both directly and via a transcriptional cascade, in roots. Analysis of grafted chimeras showed that nitrogen-deficiency-induced enhanced TGA7 expression in shoot vascular tissue promotes TGA7 protein accumulation in roots, boosting root growth and nitrate uptake. Furthermore, the loss of TGA7-mediated long-distance regulation perturbed the balance between shoot and root development under nitrogen deficiency. These findings underscore the utility of our approach for uncovering long-distance regulation in plants.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序