Efficient production of coenzyme Q(10) from acid hydrolysate of sweet sorghum juice by Rhodobacter sphaeroides

文献类型： 外文期刊

第一作者： Wang, Y.

作者： Wang, Y.;Chen, S.;Liu, J.;Zhao, G.;Lv, P.;Cai, D.

作者机构：

期刊名称：RSC ADVANCES （ 影响因子：3.361； 五年影响因子：3.39 ）

ISSN： 2046-2069

年卷期： 2019 年 9 卷 39 期

页码：

收录情况： SCI

摘要： In order to achieve efficient bioconversion of biomass-derived sugars, acid hydrolysate of sweet sorghum juice (SSJAH) containing abundant fermentable sugars was used for coenzyme Q(10) (CoQ(10)) fermentation by Rhodobacter sphaeroides CQ-09-1. The synthesis of CoQ(10) was facilitated when the initial concentration of total sugar was 80.00 g L-1. And the highest CoQ(10) titer was obtained when the pH and temperature were maintained at 7.00 and 30.00 degrees C, respectively. Moreover, corn steep powder (CSP) was proved to be an efficient nitrogen & salt supplement to SSJAH. Under the optimized conditions, the titer of CoQ(10) reached 141.95 mg L-1 in a fed-batch fermentation. The CoQ(10) titer reported was about two times higher than that obtained in the previous study using wild strains. This process introduces a potential way to produce CoQ(10) using the concept of biorefinery, while making full use of sweet sorghum juice (SSJ).

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