Genome sequencing and transcriptome analysis provide an insight into the hypoxia resistance of Channa asiatica

文献类型： 外文期刊

第一作者： Zhou, Chaowei

作者： Zhou, Chaowei;Li, Junting;Duan, Yuting;Fu, Suxing;Li, Hejiao;Zhou, Yinhua;Zhou, Xinghua;Lei, Luo;Yuan, Dengyue;Zhou, Chaowei;Li, Junting;Duan, Yuting;Fu, Suxing;Li, Hejiao;Zhou, Yinhua;Gao, He;Zhou, Xinghua;Liu, Haiping;Lei, Luo;Yuan, Dengyue;Gao, He;Liu, Haiping;Chen, Jie

作者机构：

关键词： Channa asiatica; de novo genome assembly; Transcriptome analysis; Gene family expansion; Hypoxia tolerance

期刊名称：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES （ 影响因子：8.5； 五年影响因子：8.7 ）

ISSN： 0141-8130

年卷期： 2024 年 282 卷

页码：

收录情况： SCI

摘要： Channa asiatica is an economically valuable fish species and excellent model for studying hypoxic tolerance. However, the underlying genetic and molecular mechanisms are poorly understood. In this study, we assembled a high-quality C. asiatica genome (23 chromosomes, totaling 722 Mb) using a combination of Illumina short-read, PacBio long-read, and Hi-C sequencing. Repetitive elements accounted for 28.39%of the C. asiatica genome, and 23,949 protein-coding genes were predicted, with 96.63 % of these functionally annotated. Moreover, a comparative genomic analysis of 12 fish genomes showed that gene families associated with oxygen binding and transport were expanded in C. asiatica. In addition, transcriptome analysis revealed that multiple oxidative stress pathways were activated when C. asiatica was exposed to air. In conclusion, this study provided high-quality genome assembly and transcriptome data, both serving as critical resources for researching the genetic basis of hypoxic tolerance in C. asiatica.

分类号：

  • 相关文献
作者其他论文 更多>>

微信小程序