An effective restoration of one-carbon metabolism in folate-deficient mice with a high-folate corn inbred line
文献类型： 外文期刊
第一作者： Lu, Xiaolin
作者： Lu, Xiaolin;Min, Jie;Chang, Shaoyan;Zhang, Ting;Wang, Li;Jiang, Ling;Liang, Qiuju;Zhang, Chunyi;Zhang, Qizong;Zhao, Lijiao;Huo, Junshen;Li, Yan;Zhang, Chunyi
作者机构：
关键词： Folic Acid (FA); DNA Methylation; High-Folate Corn; Long Interspersed Nucleotide Element-1 (LINE-1); Lipid Metabolism
期刊名称：JOURNAL OF FUNCTIONAL FOODS （ 影响因子：5.223； 五年影响因子：5.178 ）
ISSN： 1756-4646
年卷期： 2022 年 99 卷
页码：
收录情况： SCI
摘要： Since folic acid (FA) was officially recommended in 1998, concerns have emerged about the effect of excess FA intake, in particular with respect to negative clinical effects. Given this, a high-folate corn inbred line that we identified from a global germplasm collection was believed to become a valid alternative to FA supplementation. In this study, we proved this natural form of plant-sourced folates exhibited an effective restoration of folate deficiency. Folate metabolism and methylation modifications were restored in folate-deficient mice with folate-supplemented diets in 4 weeks. Restoration effects varies depending on folate sources, restricted retrotransposon activity and an orderly pattern of phospholipid/lipid metabolism protected by this high-folate corn partly en-sures a healthy folate status for development. Totally, we proved in mice models that this kind of folate bio-fortification corn could provide a valid alternation of FA supplementation in alleviation of folate deficiency during pregnancy.
分类号：
- 相关文献
作者其他论文 更多>>
-
Non-contact preservation of chilled chicken: extending shelf life and modulating microbial dynamics using solid spice essential oils and modified atmosphere packaging
作者：Li, Xue;Fu, Dongwen;Hu, Shuai;Huang, Jinqing;Wang, Li;Zhang, Yao;Liu, Cailing;Dong, Bo;Liu, Guangxian
关键词：Chicken breast; Bacterial community; Shelf life; Modified atmosphere packaging; Essential oil; Preservative
-
Correlation study between structural parameters of droplets and rheological properties of O/W high internal phase Pickering emulsions above the closest packing density
作者：Wang, Chenzhi;Li, Yan;Xiong, Wei;Liang, Qiang;Hua, Xin;Xuan, Pu;Yao, Yingzheng;Lin, Wei
关键词：High internal phase Pickering emulsions; Emulsion structure; Closest packing density; Confocal laser scanning microscope; Soy protein isolate nanoparticles
-
CaEch1-mediated mitophagy regulates vegetative growth, conidiation, appressorium formation, and pathogenicity in Colletotrichum camelliae
作者：Meng, Shuai;Cheng, Longjun;Chao, Shufen;Xiong, Meng;Luo, Chaoxi;Wang, Li;Chen, Ya
关键词：Anthracnose;
Colletotrichum camelliae ; CaEch1; Pathogenicity; Mitophagy -
The endosomal-vacuolar transport system acts as a docking platform for the Pmk1 MAP kinase signaling pathway in Magnaporthe oryzae
作者：Wang, Qing;Huang, Zhicheng;Li, Yan;Li, Hui;Lin, Fu-Cheng;Lu, Jianping;Wang, Jing;Cai, Yingying;Wang, Jiaoyu;Lin, Fu-Cheng;Huang, Pengyun;Liu, Xiaohong;Lin, Fu-Cheng
关键词：appressorium; endosome; MAPK; Pmk1; rice blast fungus; signal; ubiquitination; vacuole
-
OsPAD1, encoding a non-specific lipid transfer protein, is required for rice pollen aperture formation
作者：Wang, Qiming;Tian, Yunlu;Chen, Keyi;Wang, Chaolong;Yu, Xiaowen;Bai, Wenting;Zheng, Hai;You, Shimin;Hu, Yang;Lei, Dekun;Jian, Anqi;Lu, Jiayu;Yu, Hao;Jiang, Ling;Zhao, Zhigang;Wan, Jianmin;Zhu, Shanshan;Xiong, Yehui;Zhang, Xin;Ren, Yulong;Lei, Cailin;Cheng, Zhijun;Lin, Qibing;Wan, Jianmin
关键词：Sterile; Fibrillar-granular layer; Operculum; Lipid binding;
Oriza sativa -
Population sequencing of cherry accessions unravels the evolution of Cerasus species and the selection of genetic characteristics in edible cherries
作者：Lei, Yahui;Jiu, Songtao;Xu, Yan;Lv, Zhengxin;Liu, Xunju;Wang, Lei;Wang, Li;Wang, Jiyuan;Zhang, Zhuo;Wang, Shiping;Zhang, Caixi;Lei, Yahui;Dong, Xiao;Dong, Yang;Chen, Baozheng;Dong, Yang;Bernard, Anthony;Barreneche, Teresa;Elisabeth, Dirlewanger;Cai, Yuliang;Zheng, Wei;Zhang, Xu;Li, Fangdong;Li, Hongwen;Liu, Congli;Li, Ming;Wang, Jing;Zhu, Jijun;Peng, Lei;Yu, Fei;Duan, Shengchang
关键词：
Cerasus subgenus; Population structure; Genetic diversity; Edible cherries; Selection signatures -
Transcriptome Analysis Reveals the Key Genes and Pathways for Growth, Ion Transport, and Oxidative Stress in Post-Larval Black Tiger Shrimp (Penaeus monodon) Under Acute Low Salt Stress
作者：Li, Yiming;Gao, Pengcheng;Li, Yan;Sun, Zhen;Li, Longyi;Zhou, Kai;Wei, Yuxing;Yao, Zongli;Lai, Qifang;Ye, Yucong
关键词：Ion transport;
Penaeus monodon ; Low salt; Transcriptome analysis; Gene expression
