New polyketides from the starfish-derived symbiotic fungus Penicillium sp. GGF16-1-2

文献类型: 外文期刊

第一作者: He, Yu-Pei

作者: He, Yu-Pei;Feng, Chan;Zhang, Qi;Wang, Yu-Mei;Zhang, Cui-Xian;Xiang, Jun;Shao, Xue-Hua

作者机构:

关键词: Penicillium sp.; citrinin derivatives; antifungal activities

期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.7; 五年影响因子:1.7 )

ISSN: 1028-6020

年卷期: 2024 年

页码:

收录情况: SCI

摘要: One new rare carbon-bridged citrinin dimer quinocitrindimer C (1) as a pair of epimers, two new polyketide penicilliodes D (3) and E (4) together with nine known citrinin derivatives, were isolated from the fermentation broth of starfish-derived symbiotic fungus Penicillium sp. GGF16-1-2. Their structures and configurations were elucidated by comprehensively spectroscopic data analysis and electronic circular dichroism calculations. Eleven citrinin derivatives were tested by Colletotrichum gloeosporioides, and compound 2 played a significant antifungal activity against Colletotrichum gloeosporioides with LC50 value of 0.27 mu g/ml.

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