Genome-wide association analysis identify candidate genes for feed efficiency and growth traits in Wenchang chickens
文献类型： 外文期刊
第一作者： Cai, Keqi
作者： Cai, Keqi;Chang, Yuxiao;Cai, Keqi;Liu, Ranran;Cui, Huanxian;Luo, Na;Wen, Jie;Zhao, Guiping;Wei, Limin;Zhao, Guiping;Wang, Xiuping
作者机构：
关键词： Wenchang chicken; Feed efficiency trait; Growth trait; GWAS; Candidate gene
期刊名称：BMC GENOMICS （ 影响因子：3.5； 五年影响因子：4.1 ）
ISSN： 1471-2164
年卷期： 2024 年 25 卷 1 期
页码：
收录情况： SCI
摘要： BackgroundWenchang chickens are one of the most popular local chicken breeds in the Chinese chicken industry. However, the low feed efficiency is the main shortcoming of this breed. Therefore, there is a need to find a more precise breeding method to improve the feed efficiency of Wenchang chickens. In this study, we explored important candidate genes and variants for feed efficiency and growth traits through genome-wide association study (GWAS) analysis.ResultsEstimates of genomic heritability for growth and feed efficiency traits, including residual feed intake (RFI) of 0.05, average daily food intake (ADFI) of 0.21, average daily weight gain (ADG) of 0.24, body weight (BW) at 87, 95, 104, 113 days of age (BW87, BW95, BW104 and BW113) ranged from 0.30 to 0.44. Important candidate genes related to feed efficiency and growth traits were identified, such as PLCE1, LAP3, MED28, QDPR, LDB2 and SEL1L3 genes.ConclusionThe results identified important candidate genes for feed efficiency and growth traits in Wenchang chickens and provide a theoretical basis for the development of new molecular breeding technology.
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