A novel metal-organic framework based electrochemical immunosensor for the rapid detection of Salmonella typhimurium detection in milk

文献类型： 外文期刊

第一作者： Zhan, Ke

作者： Zhan, Ke;Chen, Linlin;Yu, Qiuying;Zhao, Zheng;Li, Junwei;Ren, Hongtao;Li, Shanshan;Wang, Na;Zhan, Ke;Chen, Linlin;Li, Shanshan;Yu, Qiuying;Zhao, Zheng;Li, Junwei;Ren, Hongtao;Wang, Na;Zhang, Gaiping;Zhan, Ke;Chen, Linlin;Li, Shanshan;Yu, Qiuying;Zhao, Zheng;Li, Junwei;Ren, Hongtao;Wang, Na;Zhang, Gaiping;Zhang, Gaiping;Zhan, Ke;Chen, Linlin;Li, Shanshan;Zhao, Zheng;Li, Junwei;Xing, Yunrui;Ren, Hongtao;Wang, Na;Zhang, Gaiping;Zhan, Ke;Chen, Linlin;Li, Shanshan;Yu, Qiuying;Zhao, Zheng;Li, Junwei;Ren, Hongtao;Wang, Na;Zhang, Gaiping

作者机构：

关键词： Salmonella typhimurium; Electrochemical immunosensor; Food safety; Metal -organic framework; Platinum nanoparticles; Multiwalled carbon nanotubes

期刊名称：FOOD CHEMISTRY （ 影响因子：8.8； 五年影响因子：8.6 ）

ISSN： 0308-8146

年卷期： 2024 年 444 卷

页码：

收录情况： SCI

摘要： Salmonella is one of the most prevalent pathogens causing foodborne diseases. In this study, a novel electrochemical immunosensor was designed for the rapid and accurate detection of Salmonella typhimurium (S. typhimurium) in milk. Platinum nanoparticles and Co/Zn-metal-organic framework @carboxylic multiwalled carbon nanotubes in the immunosensor acted synergistically to enhance the sensing sensitivity and stability. The materials and sensors were characterised using X-ray diffractometry, scanning electron microscopy, Fouriertransform infrared spectroscopy, differential pulse voltammetry, cyclic voltammetry, and other techniques. The optimised immunosensor showed a linear response for S. typhimurium concentrations in the range from 1.3 x 102 to 1.3 x 108 CFU mL-1, with a detection limit of 9.4 x 101 CFU mL-1. The assay also demonstrates good specificity, reproducibility, stability, and practical application potential, and the method can be extended to other foodborne pathogens.

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