Phyllaciduloids E and F, two new cleistanthane diterpenoids from the leaves of Phyllanthus acidus

文献类型： 外文期刊

第一作者： Geng, Hui-Chun

作者： Geng, Hui-Chun;Zhu, Hong-Tao;Wang, Dong;Yang, Chong-Ren;Zhang, Ying-Jun;Geng, Hui-Chun;Geng, Hui-Chun;Yang, Wei-Nong

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关键词： Phyllanthus acidus; cleistanthane diterpenoids; quantum chemical calculations; cytotoxicity

期刊名称：NATURAL PRODUCT RESEARCH （ 影响因子：2.862； 五年影响因子：2.572 ）

ISSN： 1478-6419

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收录情况： SCI

摘要： Phyllaciduloids E (1) and F (2), two new cleistanthane diterpenoids, were isolated from the leaves of Phyllanthus acidus (L.) Skeels (Phyllanthaceae). Their planar structures were established by spectroscopic analysis and comparison with literature values. The relative configurations of phyllaciduloids E and F were confirmed by DFT-NMR chemical shift calculations and subsequent CP3 probability methods. Phyllaciduloids E and F were evaluated for their cytotoxicity. However, no significant activities were detected at concentrations up to 40 mu M.

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