m(6)A-dependent mevalonate kinase in juvenile hormone synthesis pathway regulates the diapause process of bivoltine silkworm (Bombyx mori)
文献类型： 外文期刊
第一作者： Chen, Yan-Hua
作者： Chen, Yan-Hua;Jiang, Tao;Yasen, Ayinuer;Fan, Bing-Yan;Zhu, Juan;Wang, Mei-Xian;Qian, Ping;Shen, Xing-Jia;Chen, Yan-Hua;Jiang, Tao;Yasen, Ayinuer;Fan, Bing-Yan;Zhu, Juan;Wang, Mei-Xian;Qian, Ping;Shen, Xing-Jia
作者机构：
关键词： RNA N6-methyladenosine methylation; Bombyx mori; Diapause; MeRIP-Seq; Mevalonate kinase
期刊名称：MOLECULAR BIOLOGY REPORTS （ 影响因子：2.8； 五年影响因子：2.7 ）
ISSN： 0301-4851
年卷期： 2023 年
页码：
收录情况： SCI
摘要： BackgroundResearch has shown that epigenetic modification are involved the regulation of diapause in bivoltine silkworms (Bombyx mori), but it remains unclear how epigenetic modification in response to environmental signals precisely to regulate the diapause processing of bivoltine B. mori.Methods and resultsIn this study, the diapause terminated eggs of bivoltine B. mori, Qiufeng (QF) were divided into two groups: a QFHT group incubated at 25 degrees C with a natural day/night cycle to produce diapause eggs, and a QFLT group incubated at 16.5 degrees C in darkness to produce non-diapause eggs. On the 3rd day of the pupal stage, the total RNAs of the eggs were extracted and their N6-adenosine methylation (m(6)A) abundances were analyzed to explore the effects of m(6)A methylation on diapause in the silkworm. The results showed that 1984 m(6)A peaks are shared, 1563 in QFLT and 659 in QFHT. The m(6)A methylation level of the QFLT group was higher than that of the QFHT one in various signaling pathways. The m(6)A methylation rate of mevalonate kinase (MK) in the insect hormone synthesis pathway was significantly different between the two groups. The knockdown of MK by RNA interference in the pupae of QFLT resulted in females laying diapause eggs rather than non-diapause eggs after mating.Conclusionsm(6)A methylation involves in the diapause regulation of bivoltine B. mori by changing the expression levels of MK. This result provides a clearer image of the environmental signals on the regulation of diapause in bivoltine silkworms.
分类号：
- 相关文献
作者其他论文 更多>>
-
N6-methyladenosine RNA modification regulates photoperiod sensitivity in cotton
作者：He, Ying;Si, Zhanfeng;Cheng, Yu;Zhang, Jun;Jiang, Tao;Chen, Jiani;Xiong, Huifang;Zhang, Tianzhen;Hu, Yan;Mei, Gaofu;Zhang, Tianzhen;Hu, Yan
关键词：
-
Identification of "Bathed" Chinese Mitten Crabs (Eriocheir sinensis) Using Geometric Morphological Analysis of the Carapace
作者：Xu, Yiqian;Liu, Hongbo;Yang, Jian;Xue, Junren;Liu, Hongbo;Jiang, Tao;Chen, Xiubao;Yang, Jian
关键词：Eriocheir sinensis; landmark; geometric morphometrics; "introduced"/"bathed" crab; discriminant analysis; aquaculture
-
Otolith biogeochemistry reveals possible impacts of extreme climate events on population connectivity of a highly migratory fish, Japanese Spanish mackerel Scomberomorus niphonius
作者：Pan, Xindong;Tian, Yongjun;Pan, Xindong;Tian, Yongjun;Pan, Xindong;Tian, Yongjun;Pan, Xindong;Chen, Yong;Jiang, Tao;Yang, Jian
关键词：Population connectivity; ENSO; Otolith biogeochemistry; Migration; Scomberomorus niphonius
-
An innovative immunochromatographic assay employing Pt-Pd bimetallic nanoparticles as labels for the detection of foot-and-mouth disease virus serotype O
作者：Sun, Yanyan;Li, Xin;Lin, Mi;Yang, Guang;He, Huali;Bao, Yanfang;Li, Fengsong;Jiang, Tao;Lin, Mi;Jiang, Tao;Jiang, Tao
关键词：Immunochromatographic assay; Pt-Pd bimetallic nanoparticles; Peroxide-like; Foot-and-mouth disease virus type O
-
Upf2-Mediated Nonsense-Mediated Degradation Pathway Involved in Genetic Compensation of TrpA1 Knockout Mutant Silkworm (Bombyx mori)
作者：Wang, Dong-Yue;Zhu, Juan;Zhang, Yi-Zhong;Cui, Qian-Yi;Wang, Shan-Shan;Ning, Yang-Wei;Shen, Xing-Jia;Zhu, Juan;Shen, Xing-Jia
关键词：BmTrpA1; CRISPR/Cas9; Bombyx mori; genetic compensation response; nonsense-mediated mRNA degradation pathway
-
A telomere-to-telomere genome assembly of Zhonghuang 13, a widely-grown soybean variety from the original center of Glycine max
作者：Zhang, Anqi;Kong, Tangchao;Qiu, Shizheng;Guo, Jiahe;Ruan, Shuyong;Guo, Yu;Guo, Jirui;Zhang, Zhishuai;Liu, Yue;Hu, Zheng;Jiang, Tao;Liu, Yadong;Cao, Shuqi;Hu, Yang;Liu, Bo;Wang, Yadong;Sun, Baiquan;Sun, Shi;Wu, Tingting;Jiang, Bingjun;Yang, Maoxiang;Yao, Xiangyu;Han, Tianfu;Hong, Huilong
关键词：Soybean; Telomere-to-Telomere assembly; Zhonghuang 13; Structure variations
-
Unprecedented phytoplankton blooms in autumn/winter in the southern Bohai Sea (China) due to high Yellow River discharge: Implications of extreme rainfall events
作者：Ding, Xiaokun;Qin, Xiaohan;Jiang, Tao;Li, Xiangyang;Xie, Yixuan;Wei, Yuqiu;Cui, Zhengguo;Wang, Aobo;Guo, Xinyu;Xu, Xiaotao;Liu, Chenglei
关键词：Phytoplankton; Abnormal blooms; Yellow River; Bohai Sea
