Draft genome sequence analysis of a novel MLST (ST5028) and multidrug-resistant Klebsiella quasipneumoniae subsp. similipneumoniae (Kp4) strain 456S1 isolated from a pig farm in China
文献类型： 外文期刊
第一作者： Zhao, Yanan
作者： Zhao, Yanan;Liu, Lingli;Wang, Shaohui;Tian, Mingxing;Qi, Jingjing;Li, Tao;Yu, Shengqing
作者机构：
关键词： Klebsiella quasipneumoniae; Multidrug resistance; Genome analysis
期刊名称：JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE （ 影响因子：4.349； 五年影响因子：3.915 ）
ISSN： 2213-7165
年卷期： 2021 年 24 卷
页码：
收录情况： SCI
摘要： Objectives: The avian breeding industry is an important element in exposing bacteria to antibiotics. As one of the major animal welfare and economic problems for the poultry industry, multidrug-resistant Klebsiella spp. have become a substantial source of antibiotic resistance genes. In the present work, we reported the draft genome sequence of a novel multilocus sequence type (MLST) (ST5028) Klebsiella quasipneumoniae subsp. similipneumoniae (Kp4) strain 456S1, which was isolated from a pig farm in China with broad-spectrum antimicrobial activities. Methods: Classical microbiological methods were applied to isolate and identify the strain, genomic DNA was sequenced using an Illumina HiSeq platform, and the reads were de novo assembled into contigs using CLC Genomics Workbench. The assembled contigs were annotated, and whole-genome sequencing (WGS) analysis was performed.& nbsp; Results: WGS analysis revealed that the genome of strain 456S1 comprised a circular chromosome of 5,419,059 bp (GC content, 57.8%), harbouring 12 important antibiotic resistance genes: aac(6')-ib-cr, aadA16, floR, dfrA27, fosA, tet(D), blaOKP-B-3, oqxA, oqxB, qnrB6, sul1 and arr-3. The Klebsiella quasipneumoniae subsp. similipneumoniae (Kp4) 456S1 was also found to belong to a novel sequence type (ST5028) determined by MLST. Conclusion: The genome sequence reported herein will provide useful information for antibiotic resistance and pathogenic mechanisms in Klebsiella quasipneumoniae and will be a reference for comparative analysis with genomic features among different sources of clinically important multidrugresistant strains, especially among bacteria of animal and human origin. (C) 2021 The Author(s). Published by Elsevier Ltd on behalf of International Society for Antimicrobial Chemotherapy.
分类号：
- 相关文献
作者其他论文 更多>>
-
Quantitative Determination of Cd Using Energy Dispersion XRF Based on Gaussian Mixture Clustering-Multilevel Model Recalibration
作者：Gao, Yunbing;Zhao, Yanan;Pan, Yuchun;Sun, Wenbin;Zhao, Xiande;Liu, Xiaoyang;Li, Xue;Mao, Xuefei
关键词：
-
A QTL of eggplant shapes the rhizosphere bacterial community, co-responsible for resistance to bacterial wilt
作者：Gong, Chao;Li, Zhiliang;Sun, Baojuan;Luo, Wenlong;Luo, Shanwei;Chen, Shuting;Mai, Peiting;Li, Zhenxing;Li, Tao;Wang, Zhenshuo;Li, Ye;Wang, Yikui
关键词：
-
The aroA and luxS Double-Gene Mutant Strain Has Potential to Be a Live Attenuated Vaccine against Salmonella Typhimurium
作者：Zuo, Wei;Yang, Denghui;Wu, Xiaojun;Zhang, Beibei;Wang, Xinyu;Hu, Jiangang;Qi, Jingjing;Tian, Mingxing;Bao, Yanqing;Wang, Shaohui
关键词：Salmonella Typhimurium; double mutation strains; live attenuated vaccine
-
Extract of Gardenia jasminoides Ellis Attenuates High-Fat Diet-Induced Glycolipid Metabolism Disorder in Rats by Targeting Gut Microbiota and TLR4/Myd88/NF-κB Pathway
作者：Lv, Chenghao;Liu, Xin;Qin, Si;Chen, Shiyun;Yi, Yuhang;Wen, Xinnian;Qin, Si;Li, Tao
关键词：crocin; Gardenia jasminoides Ellis; glycolipid metabolism disorder; gut microbiota; TLR4/Myd88/NF-kappa B pathway
-
An Original UV Adhesive Watermelon Grafting Method, the Grafting Device, and Experimental Verification
作者：Zhang, Xin;Kong, Linghao;Lu, Hanwei;Zhang, Xin;Feng, Qingchun;Li, Tao;Jiang, Kai;Zhang, Qian
关键词：watermelon grafting; UV adhesive; fluent; VOF-DPM numerical simulation; grafting device; test
-
Tree species diversity modulates the effects of fungal pathogens on litter decomposition: evidences from an incubation experiment
作者：Guo, Lulu;Chang, Pengfei;Deng, Meifeng;Yang, Sen;Yang, Lu;Peng, Ziyang;Wang, Zhenhua;Jia, Zhou;Wang, Bin;Liu, Chao;Liu, Lingli;Guo, Lulu;Chang, Pengfei;Deng, Meifeng;Yang, Sen;Yang, Lu;Peng, Ziyang;Wang, Zhenhua;Jia, Zhou;Wang, Bin;Liu, Chao;Liu, Lingli;Guo, Lulu;Chang, Pengfei;Yang, Lu;Peng, Ziyang;Liu, Lingli;Yang, Sen;Beugnon, Remy;Saadani, Mariem;Cesarz, Simone;Eisenhauer, Nico;Bruelheide, Helge;Beugnon, Remy;Beugnon, Remy;Saadani, Mariem;Bruelheide, Helge;Wang, Zhenhua;Jia, Zhou;Wang, Bin;Cesarz, Simone;Eisenhauer, Nico
关键词：Tree species richness; Fungal pathogen infection; Litter quality; Soil organic carbon; Biodiversity-ecosystem functioning
-
Identification and Genomic Analyses of a Multidrug Resistant Avian Pathogenic Escherichia coli Coharboring mcr-1, blaTEM-176 and blaCTX-M-14 Genes
作者：Wang, Zhiyang;Wang, Xinyu;Guo, Weiqi;Wang, Di;Hu, Jiangang;Zhang, Beibei;Qi, Jingjing;Tian, Mingxing;Bao, Yanqing;Wang, Shaohui;Wang, Zhiyang;Li, Haihua;Wang, Shaohui
关键词：
