The genome sequence of the multinucleocapsid nucleopolyhedrovirus of the Chinese oak silkworm Antheraea pernyi

文献类型： 外文期刊

第一作者： Fan, Qi

作者： Fan, Qi;Li, Shuying;Wang, Linmei;Zhang, Bo;Ye, Bo;Zhao, Zhenjun;Cui, Liwang

作者机构：

关键词： Antheraea pernyi;baculovirus;genome;evolution;NUCLEAR POLYHEDROSIS-VIRUS;BOMBYX-MORI NUCLEOPOLYHEDROVIRUS;SINGLE NUCLEOCAPSID NUCLEOPOLYHEDROVIRUS;GENE ORGANIZATION;DNA-REPLICATION;BRO PROTEINS;BACULOVIRUS;IDENTIFICATION;EXPRESSION;BINDING

期刊名称：VIROLOGY （ 影响因子：3.616； 五年影响因子：3.967 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： The complete genome sequence of the Liaoning isolate of the Antheraea pernyi multinucleocapsid nucleopolyhedrovirus (AnpeMNPV) was determined. The viral genome size is 126,246 bp, relatively GC-rich (53.5% G+C), with 145 predicted open reading frames (ORFs) of more than 50 amino acids, accounting for more than 97% of the genome. 97% of the ORI's have predicted functions or homologues in other baculoviruses. There are six homologous repeat regions (hrs) and two bro homologues, which are associated with regions of genome instability. The virus lacks the p35 homologue but encodes two members of the inhibitors of apoptosis (iap) gene family. The presence of a gp64 homologue in the AnpeMNPV genome and results from gene parity plot and phylogenetic analysis using the 29 core baculovirus genes clearly classify AnpeMNPV as a group I NPV The divergence of genome sequences in two geographical NPV isolates suggests of great genetic heterogeneity of baculovirus populations in nature. (C) 2007 Elsevier Inc. All rights reserved.

分类号： R373

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