From Taxus to paclitaxel: Opportunities and challenges for urban agriculture to promote human health

文献类型： 外文期刊

第一作者： Xie, Xiulan

作者： Xie, Xiulan;Cheng, Hao;Ren, Maozhi;Xie, Xiulan;Cheng, Hao;Ren, Maozhi;Xie, Xiulan;Zhai, Yaohua;Ren, Maozhi;Wei, Wen-Hua

作者机构：

关键词： Adventitious roots; Paclitaxel biosynthesis; Synthesis strategy; Synthetic biology; Taxus x media; Urban agriculture

期刊名称：PLANT PHYSIOLOGY AND BIOCHEMISTRY （ 影响因子：5.7； 五年影响因子：6.4 ）

ISSN： 0981-9428

年卷期： 2025 年 220 卷

页码：

收录情况： SCI

摘要： Conifers of the genus Taxus are environmentally friendly plants with significant medicinal and ecological value, contributing to the enhancement of urban living environments. Paclitaxel, a compound found in Taxus, has garnered particular research interest owing to its potent anti-cancer effects. However, traditional methods of extracting paclitaxel from Taxus are not only inefficient, but also destructive and unsustainable, posing the major risk of Taxus extinction. To address this, sustainable production using modern biotechnology is crucial for the mass production of paclitaxel. Therefore, this review revisits the potential of Taxus and sustainable paclitaxel production in the context of urban agriculture. It provides a comprehensive review of widespread research efforts targeting efficient and cost-effective paclitaxel biosynthesis. We also discuss a set of innovative strategies for paclitaxel biosynthesis and suggest approaches for its industrial production based on Taxus cell-based approaches.

分类号：

  • 相关文献
作者其他论文 更多>>
  • Identification of loci and candidate genes related to nodulation in soybean

    作者：Fan, Renzhong;Wang, Jiao;Yu, Deyue;Cheng, Hao;Chao, Shengqian

    关键词：Soybean; Root nodule; Genome-wide association studies; PCA; Transcriptome analysis

  • Antibacterial Mechanism and Flavour Impact of Ultrasound and Plasma-Activated Water Combination on Aeromonas veronii in Crayfish

    作者：Xu, Weicheng;Deng, Ziai;Liu, Yi;Cheng, Hao;Ren, Maozhi;Xu, Weicheng;Qin, Zhanke;Deng, Ziai;Liu, Yi;Zhang, Haojie;Cheng, Hao;Ren, Maozhi;Sun, Rongxue;Jiang, Ning;Luo, Haibo

    关键词：A. veronii; food microbiology; sterilisation mechanism; disinfection; spoilage organisms; food safety

  • Transcriptomic and morphologic vascular aberrations underlying FCDIIb etiology

    作者：Fang, Chuantao;Sun, Licheng;Lu, Yujia;Guo, Jingjing;Mei, Xinyu;Qi, Dashi;Fang, Chuantao;Zhang, Xiaodan;Yang, Lin;Wang, Min;Tan, Yanfeng;Zhang, Jinsen;Liu, Guoping;Zhang, Fayong;Zhao, Rui;Qi, Dashi;Fang, Chuantao;Zhang, Xiaodan;Yang, Lin;Wang, Min;Tan, Yanfeng;Zhang, Jinsen;Liu, Guoping;Zhang, Fayong;Zhao, Rui;Qi, Dashi;Fang, Chuantao;Zhang, Xiaodan;Yang, Lin;Wang, Min;Tan, Yanfeng;Zhang, Jinsen;Liu, Guoping;Zhang, Fayong;Zhao, Rui;Qi, Dashi;Fang, Chuantao;Liu, Yi;Xiao, Jianbo;Gao, Xin;Zhu, Li;Ren, Maozhi;Ma, Shaojie;Zhao, Rui;Zhao, Rui

    关键词：

  • Innovative Strategies for Plant Protection: The Combination of Spray-Induced Gene Silencing and Nanotechnology

    作者：Xi, Yitao;Akram, Sawera;Yang, Xinyi;Hu, Beibei;Saddique, Muhammad Abu Bakar;Guan, Ge;Luo, Xiumei;Ren, Maozhi;Hu, Beibei;Guan, Ge;Ren, Maozhi;Tian, Donglan;Luo, Xiumei;Ren, Maozhi

    关键词：RNA interference; spray-induced gene silencing; nanotechnology; cross-kingdom RNAi; plant protection

  • Astaxanthin biosynthesis for functional food development and space missions

    作者：Xie, Xiulan;Zhong, Moyu;Huang, Xinxin;Yuan, Xinrui;Ren, Maozhi;Huang, Xinxin;Ren, Maozhi;Mahna, Nasser;Mussagy, Cassamo Ussemane

    关键词：Astaxanthin; microalgae; Haematococcuspluvialis; synthetic biology; cell factory; genetic engineering; human health; space exploration

  • The Farm Animal Genotype-Tissue Expression (FarmGTEx) Project

    作者：Fang, Lingzhao;Lin, Qing;Bai, Zhonghao;Gong, Mian;Sorensen, Peter;Sahana, Goutam;Lund, Mogens Sando;Li, Jing;Liu, Xinfeng;Teng, Jinyan;Lin, Qing;Gao, Yahui;Pan, Xiangchun;Gong, Wentao;Yuan, Xiaolong;Li, Jiaqi;Zhang, Zhe;Liu, Shuli;Yang, Jian;Liu, Shuli;Yang, Jian;Guan, Dailu;Cheng, Hao;Zhou, Huaijun;Li, Bingjie;Hou, Yali;Gong, Mian;Pan, Zhangyuan;Zhao, Fuping;Jiang, Lin;Zhao, Guiping;Zhou, Zhengkui;Zhou, Rong;Yu, Ying;Chen, Siqian;Hou, Zhuocheng;Wang, Qin;Zhang, Yi;Ding, Xiangdong;Sun, Dongxiao;Zhang, Hao;Yang, Ning;Clark, Emily L.;Smith, Jacqueline;Clark, Emily L.;Smith, Jacqueline;Rawlik, Konrad;Xiang, Ruidong;Chamberlain, Amanda J.;Goddard, Michael E.;Xiang, Ruidong;Xiang, Ruidong;Goddard, Michael E.;Chamberlain, Amanda J.;Littlejohn, Mathew;Littlejohn, Mathew;Larson, Greger;MacHugh, David E.;O'Grady, John F.;MacHugh, David E.;MacHugh, David E.;Jiang, Zhihua;Jiang, Zhihua;Zhang, Haihan;He, Xi;Zhang, Yuebo;Gao, Ning;He, Jun;Yi, Guoqiang;Liu, Yuwen;Tang, Zhonglin;Li, Kui;Zhao, Pengju;Zhou, Yang;Fu, Liangliang;Zhao, Shuhong;Zhou, Yang;Liu, Lei;Zhao, Shuhong;Wang, Xiao;Hao, Dan;Young, Robert S.;Shen, Xia;Young, Robert S.;Shen, Xia;Shen, Xia;Shen, Xia;Xia, Charley;Xia, Charley;Ma, Li;Song, Jiuzhou;Cole, John B.;Cole, John B.;Cole, John B.;Cole, John B.;Baldwin, Ransom L.;Li, Cong-jun;Van Tassell, Curtis P.;Rosen, Benjamin D.;Bhowmik, Nayan;Liu, George E.;Lunney, Joan;Liu, Wansheng;Guan, Leluo;Guan, Leluo;Zhao, Xin;Ibeagha-Awemu, Eveline M.;Luo, Yonglun;Lin, Lin;Luo, Yonglun;Lin, Lin;Canela-Xandri, Oriol;Derks, Martijn F. L.;Crooijmans, Richard P. M. A.;Godia, Marta;Madsen, Ole;Groenen, Martien A. M.;Koltes, James E.;Tuggle, Christopher K.;McCarthy, Fiona M.;Rocha, Dominique;Giuffra, Elisabetta;Amills, Marcel;Clop, Alex;Amills, Marcel;Clop, Alex;Ballester, Maria;Tosser-Klopp, Gwenola;Li, Jing;Fang, Chao;Fang, Ming;Wang, Qishan;Liu, Hehe;Deng, Juan;Jin, Long;Li, Mingzhou;Mo, Delin;Liu, Xiaohong;Chen, Yaosheng;Sun, Hui-Zeng;Li, Cong;Wang, Yu;Jiang, Yu;Wu, Dongdong;Wang, Wenwen;Fan, Xinzhong;Zhang, Qin;Hu, Xiaoxiang;Huang, Wen;Wu, Yang;Wu, Weiwei;Kasper, Claudia;Liu, Xinfeng;Yu, Xiaofei;Cui, Leilei;Cui, Leilei;Zhou, Xiang;Kim, Seyoung;Li, Wei;Im, Hae Kyung;Buckler, Edward S.;Buckler, Edward S.;Buckler, Edward S.;Ren, Bing;Ren, Bing;Schatz, Michael C.;Li, Jingyi Jessica;Palmer, Abraham A.;Palmer, Abraham A.;Frantz, Laurent;Frantz, Laurent

    关键词：

  • Microalgae: A good carrier for biological selenium enrichment

    作者：Liu, Shuang;Saddique, Muhammad Abu Bakar;Liang, Yiming;Guan, Ge;Su, Haotian;Hu, Beibei;Luo, Xiumei;Ren, Maozhi;Liu, Shuang;Saddique, Muhammad Abu Bakar;Liang, Yiming;Guan, Ge;Su, Haotian;Hu, Beibei;Luo, Xiumei;Ren, Maozhi;Guan, Ge;Su, Haotian;Hu, Beibei;Ren, Maozhi;Yang, Songqi

    关键词：Selenium-rich microalgae; Selenium metabolism; Selenoproteins; Nano-selenium

微信小程序