Sesquiterpene Lactams and Lactones With Antioxidant Potentials From Atractylodes macrocephala Discovered by Molecular Networking Strategy
文献类型： 外文期刊
第一作者： Wang, Pan
作者： Wang, Pan;Zhang, Xiao-wei;Sun, Yi-ran;Feng, Qing-mei;Li, Zhong-hua;Xu, Jiang-yan;Xie, Zhi-shen;Zhang, Zhen-qiang;Wang, Pan;Zhao, Yi-nan;Xu, Rui-zhu;Heng-chao, E.
作者机构：
关键词： sesquiterpene lactones; atractylenolactam; Atractylodes macrocephala; molecular networking; antioxidant activity
期刊名称：FRONTIERS IN NUTRITION （ 影响因子：6.59； 五年影响因子：6.873 ）
ISSN： 2296-861X
年卷期： 2022 年 9 卷
页码：
收录情况： SCI
摘要： Atractylodes macrocephala rhizome (called Bai-zhu in China) has a long history as a functional food and herbal medicine in East Asia, especially China. Sesquiterpenoids are one of the main active compounds of Atractylodes macrocephala rhizome. This study aimed to explore the unknown sesquiterpenoids of A. macrocephala rhizome using a molecular networking strategy. Two new nitrogen-containing sesquiterpenoids, atractylenolactam A (1) and atractylenolactam B (2), and 2 new sesquiterpene lactones, 8-methoxy-atractylenolide V (6) and 15-acetoxyl atractylenolide III (7), along with 12 known analogs (3-5 and 8-16) were discovered and isolated. All the structures were assigned based on detailed spectroscopic analyses. The absolute configurations of 1, 2, 6, and 7 were established by time-dependent density functional theory ECD (TDDFT-ECD) calculations. All these compounds had different degrees of concentration-dependent activating effects on nuclear-factor-E2-related factor-2 (Nrf2).
分类号：
- 相关文献
作者其他论文 更多>>
-
Characterization of lipids in Guangdong small-ear spotted pig and their crossbreeds during cold storage revealed by LC-MS-based method
作者：Huang, Wenyi;Li, Linfeng;Wang, Pan;Liu, Huilin;Liu, Midi;Meng, Fanming;Cheng, Leiyan;Hu, Bin;Zeng, Jianhua;Yang, Linfang
关键词：Pork; Cold storage; Lipidomics; Differential lipids; Meat quality
-
Regenerable Biochar Catalyst from Biogas Residue for Peroxymonosulfate Activation in Bisphenol A-Containing Wastewater Treatment
作者：Pan, Yating;Liu, Xiang;Yang, Xue;Wang, Pan;Duan, Nina;Wei, Haijuan;Lin, Miao
关键词：biogas residue; biochar; wastewater; peroxymonosulfate; advanced oxidation process; catalyst regeneration
-
Evolution of foraging behaviour induces variable complexity-stability relationships in mutualist-exploiter-predator communities
作者：Wang, Lin;Wang, Lin;Li, Jia;Wang, Lin;Wang, Ting;Zhang, Xiao-Wei;Lin, Xiao-Fen;Liao, Jin-Bao;Liao, Jin-Bao;Wang, Rui-Wu
关键词：
-
Modeling and Optimization of Microwave Vacuum Drying for Pinelliae Rhizoma: Integrating Drying Kinetics, Artificial Neural Networks, and Quality Preservation
作者：Wang, Pan;Yang, Xiaoping;Huang, Xiaopeng;Ma, Guojun;Zhu, Zewen;Xu, Yanrui;Zang, Zepeng;Liu, Xu;Zhang, Shidong;Wang, Siqi;Wang, Ming
关键词：artificial neural networks; drying characteristics; microstructure; microwave vacuum drying; Pinellia ternata (Thunb.) Breit; Pinelliae Rhizoma
-
A chromosome-level genome assembly and annotation of the Pseudorasbora elongata (Cypriniformes: Cyprinidae)
作者：Wang, Pan;Yin, Denghua;Jiang, Min;Xie, Lingli;Liu, Jie;Shao, Yan;Liu, Kai;Chen, Yukuan;Liu, Kai;Wang, Xinyue
关键词：
-
Gut microbiota and metabolic profile affected by pectic domains during in vitro rat fecal fermentation: A comparative study between different glycans rich in pectic monosaccharides
作者：Zhao, Yuanyuan;Wang, Pan;Wang, Dan;Zhao, Wenting;Wang, Junjuan;Ge, Zhiwen;Zhao, Xiaoyan;Liu, Ye
关键词：Pectin; Structural domains; In vitro fecal fermentation; Quantitative microbiome; Untargeted metabolomics; Structure-function relationship
-
Advancements in the Structure, Spatial Configuration, Functional Properties, and Dairy Applications of Lactic Acid Bacteria Exopolysaccharides
作者：Ge, Zhiwen;Wang, Dan;Zhao, Wenting;Wang, Pan;Zhao, Xiaoyan
关键词：Lactic acid bacteria; exopolysaccharides; biosynthesis pathway; structural characterization; functional activities
