Triterpenoid saponins from Bupleurum marginatum and their anti-liver fibrotic activities

文献类型: 外文期刊

第一作者: Luo, Ke

作者: Luo, Ke;Dai, Rong-Ji;Zeng, Yan-Bo;Deng, Yu-Lin;Lv, Fang;Zeng, Yan-Bo;Chang, Wen-Jun

作者机构:

关键词: Bupleurum marginatum; triterpenoid saponins; structural elucidation; anti-liver fibrotic activity

期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.7; 五年影响因子:1.7 )

ISSN: 1028-6020

年卷期: 2024 年

页码:

收录情况: SCI

摘要: A new triterpenoid saponin (1), along with five known compounds (2-6), was isolated from Bupleurum marginatum Wall. ex DC, of which compounds 2-4 were obtained for the first time from this plant. The structures were confirmed by the analysis of 1D, 2D NMR, and HR-ESIMS data, and comparison with previous spectral data. Anti-liver fibrotic activities of the isolates were determined as proliferation inhibition of LPS-induced activation of HSC-T6 in vitro.

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