Novel Bioactive Natural Products from Marine-Derived Penicillium Fungi: A Review (2021-2023)
文献类型: 外文期刊
第一作者: Lv, Fang
作者: Lv, Fang;Zeng, Yanbo;Zeng, Yanbo
作者机构:
关键词: marine-derived Penicillium; marine natural products; polyketides; antibacterial activity; cytotoxicity
期刊名称:MARINE DRUGS ( 影响因子:5.4; 五年影响因子:5.5 )
ISSN:
年卷期: 2024 年 22 卷 5 期
页码:
收录情况: SCI
摘要: Marine-derived Penicillium fungi are productive sources of structurally unique and diverse bioactive secondary metabolites, representing a hot topic in natural product research. This review describes structural diversity, bioactivities and statistical research of 452 new natural products from marine-derived Penicillium fungi covering 2021 to 2023. Sediments are the main sources of marine-derived Penicillium fungi for producing nearly 56% new natural products. Polyketides, alkaloids, and terpenoids displayed diverse biological activities and are the major contributors to antibacterial activity, cytotoxicity, anti-inflammatory and enzyme inhibitory capacities. Polyketides had higher proportions of new bioactive compounds in new compounds than other chemical classes. The characteristics of studies in recent years are presented.
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