Association of thyroglobulin gene variants with carcass and meat quality traits in beef cattle

文献类型： 外文期刊

第一作者： Hou, Guan-Yu

作者： Hou, Guan-Yu;Yuan, Zheng-Rong;Zhang, Lu-Pei;Li, Jun-Ya;Gao, Xue;Gao, Hui-Jiang;Xu, Shang-Zhong;Hou, Guan-Yu;Zhou, Han-Lin;Wang, Dong-Jing;Hou, Guan-Yu;Xu, Shang-Zhong

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关键词： meat quality trait;homozygote genotype;carcass quality trait

期刊名称：MOLECULAR BIOLOGY REPORTS （ 影响因子：2.316； 五年影响因子：2.357 ）

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收录情况： SCI

摘要： Thyroid hormones play an important role in regulating metabolism and can affect homeostasis of fat deposition. The gene encoding thyroglobulin (TG), producing the precursor for thyroid hormones, has been proposed as a positional and functional candidate gene for a QTL with an effect on fat deposition. In the present study, we identified 6 novel SNPs at the 3' flanking region of the TG gene. The SNP marker association analysis indicated that the T354C, G392A, A430G and T433G SNP markers were significantly associated with marbling score (P < 0.05). Animals with the new homozygote genotype had higher marbling score than those with the other genotypes. Otherwise, the linkage disequilibrium analysis indicated that these four SNPs were completely linked (r (2) = 1). Results from this study suggest that TG gene-specific SNP may be a useful marker for meat quality traits in future marker assisted selection programs in beef cattle.

分类号： Q7

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