Distribution and linkage disequilibrium analysis of polymorphisms of MC4R, LEP, H-FABP genes in the different populations of pigs, associated with economic traits in DIV2 line

文献类型： 外文期刊

第一作者： Chao, Zhe

作者： Chao, Zhe;Wang, Feng;Wei, Li-Min;Sun, Rui-Ping;Liu, Hai-Long;Liu, Quan-Wei;Zheng, Xin-Li;Deng, Chang-Yan;Deng, Chang-Yan

作者机构：

关键词： MC4R;LEP;H-FABP;Multiplex PCR;Linkage disequilibrium

期刊名称：MOLECULAR BIOLOGY REPORTS （ 影响因子：2.316； 五年影响因子：2.357 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： PCR-RFLP was used to analyze the polymorphisms of MC4R, LEP, H-FABP genes in a swine breed composite (DIV2) and 4 swine breeds (Yorkshire, Landrace, Meishan, Bamei). The association study of these polymorphisms with several economic traits was carried out on a DIV2 population. The results obtained showed that MC4R/TaqI genotype had an effect for average backfat thickness (P < 0.05) and lean meat percentage (P < 0.05). At locus LEP/HinfI animals of AA genotype had lower test daily gain than that of BB (P < 0.01) or AB genotype (P < 0.05). At the H-FABP/HaeIII locus lean meat percentage of the individuals with genotype DD were higher than that with genotype dd (P < 0.05). Linkage disequilibrium analysis among MC4R, LEP and H-FABP revealed that these genes were independent. This represented two or more genes that could be combined together within one genotype in order to facilitate breeding for objective traits. In addition, a method allowing simultaneous detection of fragments of MC4R and LEP gene was developed.

分类号： Q7

  • 相关文献

[1]Genome-wide introgression lines and their use in genetic and molecular dissection of complex phenotypes in rice (Oryza sativa L.). Li, ZK,Fu, BY,Gao, YM,Xu, JL,Ali, J,Lafitte, HR,Jiang, YZ,Rey, JD,Vijayakumar, CHM,Maghirang, R,Zheng, TQ,Zhu, LH.

[2]Associations of A-FABP and H-FABP Markers with the Content of Intramuscular Fat in Beijing-You Chicken. Ye, M. H.,Chen, J. L.,Zhao, G. P.,Zheng, M. Q.,Wen, J.,Ye, M. H..

[3]Generation of a recombinant rabies Flury LEP virus carrying an additional G gene creates an improved seed virus for inactivated vaccine production. Tao, Lihong,Ge, Jinying,Wang, Xijun,Wen, Zhiyuan,Zhai, Hongyue,Hua, Tao,Zhao, Bolin,Kong, Dongni,Bu, Zhigao,Yang, Chinglai. 2011

[4]Polymorphisms in MC4R gene and correlations with economic traits in cattle. Huang, Meng,Xu, Shang Zhong,Huang, Meng,Gao, Xue,Li, Jun Ya,Ren, Hong Yan,Chen, Jin Bao,Xu, Shang Zhong.

[5]Genetic Diversity of the Melanocortin 4 Receptor (MC4R) Gene and its Association with Slaughter Traits in the Landes Goose. Huang, Yi,Wang, Yan,Liu, Yiping,Huang, Yi,He, Daqian. 2010

[6]Genetic Polymorphisms of Mc4R and IGF2 Gene Association with Feed Conversion Efficiency Traits in Beef Cattle. Du, Xin-hua,Chen, Cui,Yuan, Zheng-rong,Zhang, Li-min,Chen, Xiao-jie,Wang, Yan-hui,Gao, Xue,Zhang, Lu-pei,Gao, Hui-jiang,Li, Jun-ya,Xu, Shang-zhong. 2013

[7]HSF IS THE MOST IMPORTANT TRANSCRIPTIONAL FACTOR FOR PORCINE MC4R PROMOTER. Zhang, D. J.,Liu, D.,Wang, L.,Zhang, X. H.,Bie, S.. 2012

[8]Molecular characterization of CART, AgRP, and MC4R genes and their expression with fasting and re-feeding in common carp (Cyprinus carpio). Wan, Yumei,Zhang, Yan,Ji, Peifeng,Li, Yan,Xu, Peng,Sun, Xiaowen,Wan, Yumei,Li, Yan,Sun, Xiaowen.

[9]Three novel MC4R SNPs associated with growth traits in Hu sheep and East Friesian x Hu crossbred sheep. Wang, Yalei,Wang, Chunling,Zhang, Xiaojian,Wang, Ziyu,Mao, Dagan,Zhang, Jun,Meng, Chunhua,Cao, Shaoxian,Fang, Yongfei.

[10]Qualitative and quantitative PCR methods for event-specific detection of genetically modified cotton Mon1445 and Mon531. Yang, LT,Pan, AH,Zhang, KW,Yin, CS,Qian, BJ,Chen, JX,Huang, C,Zhang, DB. 2005

[11]Development of an allele-specific marker for Glu-B3 alleles in common wheat and establishment of a multiplex PCR assay. Sui, Xinxia,Wang, Linhai,Xia, Xianchun,He, Zhonghu,Sui, Xinxia,Wang, Zhenlin,He, Zhonghu. 2010

[12]Response surface methodology to design a selective co-enrichment broth of Escherichia coli, Salmonella spp. and Staphylococcus aureus for simultaneous detection by multiplex PCR. Zhang, Qiao Yan,Zhou, Yu,Wang, Xiao Fu,Xu, Jun Feng,Zhou, Wen Wu. 2012

[13]Establishment of a Multiplex PCR and an Investigation of Co-Infection Rate of WSSV and IHHNV in Penaeid vannamei in Northern of Jiangsu. Chen, Yi-Bing,Gao, Song,Zhou, Jun-Fang,Wan, Xi-He. 2012

[14]Identification and Quantification of Three Genetically Modified Insect Resistant Cotton Lines Using Conventional and TaqMan Real-Time Polymerase Chain Reaction Methods. Yang, LT,Pan, AH,Zhang, KW,Guo, JC,Yin, CS,Chen, JX,Huang, C,Zhang, DB.

[15]Rapid diagnosis of goose viral infections by multiplex PCR. Chen, Zongyan,Li, Chuanfeng,Li, Guoxin,Yu, Hai,Jiang, Yifeng,Yan, Liping,Meng, Chunchun,Zhou, Yanjun,Tong, Guangzhi,Liu, Guangqing.

[16]Development of a multiplex PCR assay for detection and discrimination of Theileria annulata and Theileria sergenti in cattle. Junlong, Liu,Li, Youquan,Liu, Aihong,Guan, Guiquan,Xie, Junren,Yin, Hong,Luo, Jianxun,Junlong, Liu,Li, Youquan,Liu, Aihong,Guan, Guiquan,Xie, Junren,Yin, Hong,Luo, Jianxun.

[17]Development of one-tube multiplex polymerase chain reaction (PCR) for detecting Mycobacterium bovis. Quan, Zhang,Haiming, Tan,Xiaoya, Cai,Weifeng, Yuan,Hong, Jia,Hongfei, Zhu.

[18]A multiplex reverse transcription-PCR assay for the detection of influenza A virus and differentiation of the H1, H3, H5 and H9 subtypes. Wu, Ling,Ding, Longfei,Pei, Zenglin,Pan, Zishu,Huo, Xixiang,Wen, Guoyuan.

[19]Development and characterization of four moderate multiplex microsatellite panels in crucian carp (Carassius auratus). Cheng, Lei,Lu, Cui-Yun,Li, Chao,Sun, Xiao-Wen,Zhang, Yan. 2013

[20]Rapid identification of deer products by multiplex PCR assay. Zha, Dai-Ming,Xing, Xiu-Mei,Yang, Fu-He,Zha, Dai-Ming,Zha, Dai-Ming,Xing, Xiu-Mei,Yang, Fu-He,Zha, Dai-Ming,Xing, Xiu-Mei,Yang, Fu-He.

作者其他论文 更多>>

微信小程序