Identification of a transparent mutant tiger barb Puntius tetrazona and its use for in vivo observation of a Pleistophora sp (Microsporidia) infection

文献类型： 外文期刊

第一作者： Li, K. B.

作者： Li, K. B.;Chang, O. Q.;Wang, F.;Liu, C.;Wang, Q.;Liang, F. L.;Ma, B. Y.;Wu, S. Q.

作者机构：

关键词： alleles;aquatic animals;aquatic organisms;genes;identification;phenotypes;protozoal infections;Cyprinidae;Pleistophora;Cypriniformes;Osteichthyes;fishes;vertebrates;Chordata;animals;aquatic animals;aquatic organisms;eukaryotes;Pleistophoridae;Microspora;Protozoa;invertebrates;Cyprinidae;aquatic species;protozoal diseases;Puntius;Puntius tetrazona

期刊名称：JOURNAL OF FISH BIOLOGY （ 影响因子：2.051； 五年影响因子：2.25 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： A transparent mutant tiger barb Puntius tetrazona was identified and characterized by its transparent body, which allows clear visualization of internal organs. Hybridization of this mutant with the albino variant produces a transparent and albinoid double phenotype, and the transparency of this mutant is controlled by a recessive allele. Light microscopic and ultrastructural examinations show that in contrast to normal individuals, transparent mutants lack iridophores, and light penetrates unimpeded through the body. Pleistophora sp. infection was observed in vivo, allowing live observation of parasite dissemination and the consequent pathological alterations in the fish body as well as the simultaneous acquisition of data on the dynamics and spatial pattern of pathogenic invasion. It is superior to common fish models, as dynamic experimental data can be obtained from individual fish.

分类号： Q959.4

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