Construction and characterization of the infectious clone of Reticuloendotheliosis virus carrying a genetic marker
文献类型: 外文期刊
第一作者: Deng, Xiaoyun
作者: Deng, Xiaoyun;Qi, Xiaole;Wu, Guan;Gao, Yulong;Qin, Liting;Wang, Yongqiang;Gao, Honglei;Wang, Xiaomei
作者机构:
关键词: Genetic marker;Genome;HLJR0901;Infectious clone;Reticuloendotheliosis virus (REV)
期刊名称:VIRUS RESEARCH ( 影响因子:3.303; 五年影响因子:3.445 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: Reticuloendotheliosis virus (REV) causes an immunosuppressive and oncogenic disease, which posed substantial threats to the commercial poultry industry. However, researches on the molecular epidemiology and the pathogenic mechanism of REV are still scant. In this study, a full-length genome cDNA of Reticuloendotheliosis virus (REV) strain HLJR0901, which was isolated from layer in China, was cloned, sequenced, and analyzed. The genome of HLJR0901 was 8284. bp long, and the GenBank accession number is GQ415646. Sequence analysis showed that HLJR0901 was more similar to some REV strains that are common in the USA and Taiwan than to the early Chinese REV isolate. Next, the first efficient and genetically stable infectious clone with the genetic markers of the layer strain of REV was developed. The rescued and parental viruses had similar biological characteristics in vitro and in vivo. This study not only contributes to novel molecular epidemiology data, but also facilitates researching the gene functions and evolution of REV.
分类号: R37
- 相关文献
作者其他论文 更多>>
-
Genome-wide analysis of the FKBP gene family and the potential role of GhFKBP 13 in chloroplast biogenesis in upland cotton
作者:Liu, Jianguang;Geng, Zhao;Zhao, Guiyuan;Li, Mengzhe;An, Zetong;Zhang, Hanshuang;Wang, Yongqiang
关键词:
Gossypium hirsutum ;GhFKBP s; Chloroplast biogenesis; Starch and sucrose metabolism -
Marek's disease virus protein kinase US3 inhibits DNA-sensing antiviral innate immunity via abrogating activation of NF-κB
作者:Li, Kai;Liu, Rui;Liu, Yongzhen;Gao, Li;Liu, Changjun;Zhang, Yanping;Qi, Xiaole;Cui, Hongyu;Wang, Suyan;Chen, Yuntong;Duan, Yulu;Gao, Yulong;Wang, Xiaomei;Li, Kai;Li, Kai;Wang, Xiaomei
关键词:Marek's disease virus; US3; innate immunity; DNA sensing; NF-kappa B
-
Long-Term Crop Rotation Revealed the Relationship Between Soil Organic Carbon Physical Fraction and Bacterial Community at Aggregate Scales
作者:Meng, Xianghai;Wang, Baicheng;Zhang, Xingzhe;Liu, Chunguang;Yang, Bing;Wang, Wenhui;Xu, Dehai;Zhang, Shuai;Wang, Xiaomei;Ji, Jinghong;Hao, Xiaoyu;Cao, Minghui;Wang, Yuming;Wang, Yuming
关键词:aggregate; bacterial community; long-term crop rotation; soil organic carbon
-
MPF Regulates Oocyte and Embryo Development During Parthenogenesis Induction in Silkworm, Bombyx mori
作者:Ma, Chenkai;Xu, Fang;Hu, Chengjie;Yu, Wei;Xu, Xia;Ma, Chenkai;Xu, Fang;Hu, Chengjie;Cui, Chunguang;Du, Xin;Chen, Jine;Zhu, Linbao;Yu, Shaofang;He, Xingjian;Wang, Yongqiang;Xu, Xia
关键词:MPF; enzyme activity; embryo development; parthenogenesis;
Bombyx mori -
N6-methyladenosine modification of the subgroup J avian leukosis viral RNAs attenuates host innate immunity via MDA5 signaling
作者:Yu, Mengmeng;Zhang, Li;Wang, Ying;Wang, Suyan;Liu, Yongzhen;Liu, Peng;Chen, Yuntong;Guo, Ru;Meng, Lingzhai;Zhang, Tao;Fan, Wenrui;Qi, Xiaole;Duan, Yulu;Zhang, Yanping;Cui, Hongyu;Gao, Yulong;Gao, Yulong;Gao, Yulong
关键词:
-
Decreased Cdk2 Activity Hindered Embryonic Development and Parthenogenesis Induction in Silkworm, Bombyx mori L.
作者:Hu, Chengjie;Jiang, Yonghou;Ma, Chenkai;Xu, Fang;Yu, Wei;Xu, Xia;Hu, Chengjie;Ma, Chenkai;Xu, Fang;Cui, Chunguang;Du, Xin;Chen, Jine;Zhu, Linbao;Yu, Shaofang;He, Xingjian;Wang, Yongqiang;Xu, Xia
关键词:Cdk2; AUZ454; oocytes; embryo; silkworm
-
Development of an improved reverse genetics system for avian metapneumovirus (aMPV): A novel vaccine vector protects against aMPV and infectious bursal disease virus
作者:Meng, Lingzhai;Chen, Yuntong;Yu, Mengmeng;Liu, Peng;Qi, Xiaole;Xue, Xiaoxiao;Guo, Ru;Zhang, Tao;Hu, Mingxue;Fan, Wenrui;Wang, Ying;Wang, Suyan;Zhang, Yanping;Liu, Yongzhen;Duan, Yulu;Cui, Hongyu;Gao, Yulong;Gao, Yulong
关键词:avian metapneumovirus; reverse genetics system; insertion site; protection; vector vaccines