Molecular epidemiological investigation of porcine reproductive and respiratory syndrome virus in Northwest China from 2007 to 2010

文献类型： 外文期刊

第一作者： Shang, Youjun

作者： Shang, Youjun;Wang, Guangxiang;Tian, Hong;Yin, Shuanghui;Du, Ping;Wu, Jinyan;Chen, Yan;Yang, Shunli;Jin, Ye;Zhang, Keshan;Liu, Xiangtao

作者机构：

关键词： China;Molecular epidemiology;Mutation;Porcine reproductive and respiratory syndrome

期刊名称：VIRUS GENES （ 影响因子：2.332； 五年影响因子：2.0 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Porcine reproductive and respiratory syndrome (PRRS) is an economically important swine disease affecting swine worldwide. Northwest China has a sparse pig population and there is no comprehensive information currently available on PRRSV infection. In this study, we analyzed the epidemiological features and genetic diversity of PRRSV from this region. 322 field-isolated tissues or serum samples were collected from aborted pig fetuses or pigs with respiratory disease from 15 herds, twice over a period of 2 years. PRRSV infection was determined and virus strains were classified by the sequencing of GP5. We found that 35.9 % of the animals were PRRSV-positive, and the average prevalence in 2007-2008 and 2009-2010 was 46.5 and 29.3 %, respectively. To further investigate the genetic divergence of PRRSV samples collected from 2007 to 2010, 32 strains were isolated for GP5 sequencing and analysis, and phylogenetic trees were created based on GP5 amino acid sequences. All PRRSVs were of the North American genotype and belonged to the highly pathogenic HP-PRRSV subgenotype. Isolates from the Xinjiang province formed a tightly clustered branch and were closely related to an evolutionary intermediate subgroup isolate. Virus sequences from 2007 to 2008 were compared with those from 2009 to 2010 from the same herd. New mutations were found in isolates after 2009 and focused on nucleotides in the GP5 antibody decoy epitope. PRRSV strains in Northwest China from 2007 to 2010 were similar to those from other regions of China, with some regional characteristics. These results contribute to the knowledge of PRRSV epidemiology in China.

分类号： R37

  • 相关文献

[1]Geometrical Stuidy on FMDV Genome Based on Z-Curve. Tang, Hua,Liu, Xin-Sheng,Fang, Yu-Zhen,Pan, Li,Zhang, Zong-Wang,Zhou, Peng,Lv, Jian-Liang,Jiang, Shou-Tian,Wang, Yong-Lu,Zhang, Yong-Guang. 2012

[2]Polymorphic Study of FecX(G), FecG(H) and Fec(B) Mutations in Four Domestic Sheep Breeds in the Lower Yellow River Valley of China. Zhang, Chuan-Sheng,Geng, Li-Ying,Du, Li-Xin. 2011

[3]Enhanced thermostability of methyl parathion hydrolase from Ochrobactrum sp. M231 by rational engineering of a glycine to proline mutation. Tian, Jian,Wang, Ping,Gao, Shan,Chu, Xiaoyu,Wu, Ningfeng,Fan, Yunliu.

[4]Generation and characterization of low phytic acid germplasm in rice (Oryza sativa L.). Liu, Qing-Long,Xu, Xiu-Hong,Ren, Xue-Liang,Fu, Hao-Wei,Wu, Dian-Xing,Shu, Qing-Yao.

[5]Plasmid containing CpG motifs enhances the efficacy of porcine reproductive and respiratory syndrome live attenuated vaccine. Guo, Xiaoyu,Hou, Shaohua,Zhu, Hongfei,Guo, Xiaoyu,Sanchez-Vizcaino, J. M.,Guo, Xiaoyu,Sanchez-Vizcaino, J. M.,Zhang, Quan,Zhai, Guoqin. 2011

[6]Microbial ecology of swine farms and PRRS vaccine vaccination strategies. Zhao, Zhanzhong,Lai, Zhi,Guo, Xin,Yang, Hanchun,Zhao, Zhanzhong,Lai, Zhi,Guo, Xin,Yang, Hanchun,Zhao, Zhanzhong,Qin, Yuming,Wang, Liyong,Peng, Liying,Cai, Xuehui. 2012

[7]A conjugate protein containing HIV TAT, ISG20, and a PRRSV polymerase binding inhibits PRRSV replication and may be a novel therapeutic platform. Liu, Ke,Li, Yuming,Huan, Beili,Shao, Donghua,Wei, Jianchao,Qiu, Yafeng,Li, Beibei,Tong, Guangzhi,Ma, Zhiyong,Zhou, Bin,Wang, Feifei,Qian, Yingjuan,Jung, Yong-Sam,Miao, Denian.

[8]Development of an immunochromatographic strip for detection of antibodies against porcine reproductive and respiratory syndrome virus. Li, Huawei,Ji, Pengchao,Zhou, Enmin,Zhang, Gaiping,Yang, Jifei,Bao, Dengke,Hou, Jie,Zhi, Yubao,Yang, Yanyan,Qiao, Songlin,Zhang, Gaiping,Zhang, Gaiping,Li, Huawei.

[9]Molecular epidemiology of hydropericardium syndrome outbreak-associated serotype 4 fowl adenovirus isolates in central China. Zhang, Teng,Zhang, Teng,Jin, Qianyue,Ding, Peiyang,Chai, Yongxiao,Li, Yafei,Liu, Xiao,Luo, Jun,Zhang, Gaiping,Chai, Yongxiao,Liu, Xiao,Zhang, Gaiping,Ding, Peiyang,Li, Yafei,Wang, Yinbiao,Jin, Qianyue,Zhang, Gaiping. 2016

[10]The detection of porcine circovirus 3 in Guangxi, China. Wen, S.,Sun, W.,Li, Z.,Zhuang, X.,Zhao, G.,Xie, C.,Jing, J.,Xiao, P.,Wang, M.,Han, J.,Lu, H.,Jin, N.,Sun, W.,Wang, M.,Li, Z.,Zhao, G.,Zheng, M.,Ren, J.,Liu, H.. 2018

[11]The prevalent status and genetic diversity of porcine reproductive and respiratory syndrome virus in China: a molecular epidemiological perspective. Guo, Zhenhua,Chen, Xin-xin,Li, Rui,Qiao, Songlin,Zhang, Gaiping,Zhang, Gaiping,Zhang, Gaiping. 2018

[12]Detection of Latent Infection of Wheat Leaves Caused by Blumeria graminis f.sp tritici Using Nested PCR. . 2010

[13]Real-time PCR quantification of latent infection of wheat powdery mildew in the field. Zhou, Yilin,Zeng, Xiaowei,Duan, Xiayu,Cao, Xueren,Luo, Yong,Song, Yuli,Wang, Baotong.

[14]Molecular epidemiological and phylogenetic analyses of canine parvovirus in domestic dogs and cats in Beijing, 2010-2013. Wu, Jing,Gao, Xin-Tao,Hou, Shao-Hua,Guo, Xiao-Yu,Yuan, Wei-Feng,Xin, Ting,Zhu, Hong-Pei,Jia, Hong,Yang, Xue-Shong.

[15]Identification and characterization of a novel subgenotype of bovine viral diarrhea virus isolated from dairy cattle in Northwestern China. Gong, Xiaowei,Cao, Xiaoan,Zheng, Fuying,Chen, Qiwei,Zhou, Jizhang,Yin, Hong,Cai, Xuepeng,Liu, Lihong. 2013

[16]Common occurrence of a unique Cryptosporidium ryanae variant in zebu cattle and water buffaloes in the buffer zone of the Chitwan National Park, Nepal. Dearen, Theresa K.,Xiao, Lihua,Feng, Yaoyu,Feng, Yaoyu,Karna, Sandeep Raj,Singh, Dinesh Kumar,Adhikari, Lekh Nath,Shrestha, Aruna.

[17]Molecular epidemiology of Aleutian mink disease virus in China. Wang, Zhenjun,Wu, Wei,Hu, Bo,Zhang, Hailing,Bai, Xue,Zhao, Jianjun,Zhang, Lei,Yan, Xijun.

[18]Emerging and endemic types of Ostreid herpesvirus 1 were detected in bivalves in China. Bai, Changming,Wang, Chongming,Xia, Junyang,Zhang, Shuai,Huang, Jie,Bai, Changming,Wang, Chongming,Huang, Jie,Sun, Hailin.

[19]Genetic differentiation in seven geographic populations of the fleshy shrimp Penaeus (Fenneropenaeus) chinensis based on microsatellite DNA. Meng, Xian Hong,Wang, Qing Yin,Liu, Ping,Kong, Jie,Meng, Xian Hong,Jang, In Kwon.

[20]Molecular characterization of novel haplotypes of eIF4E family in Chinese cabbage (Brassica rapa L. ssp pekinensis). Liu, Shuan-Tao,Zhang, Zhi-Gang,Li, Qiao-Yun,Wang, Shu-Fen,Zhao, Zhi-Zhong,Lu, Jin-Dong,Xu, Wen-Ling,Liu, Xian-Xian,Fu, Wei-Min. 2013

作者其他论文 更多>>

微信小程序