Intranasal immunisation with Stx2B-Tir-Stx1B-Zot protein leads to decreased shedding in goats after challenge with Escherichia coli O157:H7
文献类型： 外文期刊
第一作者： Zhang, X-H.
作者： Zhang, X-H.;He, K-W.;Zhao, P-D.;Ye, Q.;Luan, X-T.;Yu, Z-Y.;Wen, L-B.;Ni, Y-X.;Li, B.;Wang, X-M.;Guo, R-L.;Zhou, J-M.;Mao, A-H.
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期刊名称：VETERINARY RECORD （ 影响因子：2.695； 五年影响因子：2.797 ）
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收录情况： SCI
摘要： Other than cattle, small domestic ruminants (sheep and goats) have been found to be an important reservoir of Escherichia coli 0157-H7. Reducing E coli O157-.H7 excretion by these animals could play a key role in the prevention and control of human infections. The aim of this study was to determine whether vaccination of goats with a recombinant Stx2B-Tir-StxlB-Zot protein was capable of reducing faecal shedding of E coli O157:H7 in an oral infection model.
分类号： S85
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