Recent advances in the development of new transgenic animal technology

文献类型： 外文期刊

第一作者： Miao, Xiangyang

作者： Miao, Xiangyang;Miao, Xiangyang

作者机构：

关键词： Gene targeting;Induced pluripotent stem cells;RNA interference;Transgenic technologies

期刊名称：CELLULAR AND MOLECULAR LIFE SCIENCES （ 影响因子：9.261； 五年影响因子：9.073 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： Transgenic animal technology is one of the fastest growing biotechnology areas. It is used to integrate exogenous genes into the animal genome by genetic engineering technology so that these genes can be inherited and expressed by offspring. The transgenic efficiency and precise control of gene expression are the key limiting factors in the production of transgenic animals. A variety of transgenic technologies are available. Each has its own advantages and disadvantages and needs further study because of unresolved technical and safety issues. Further studies will allow transgenic technology to explore gene function, animal genetic improvement, bioreactors, animal disease models, and organ transplantation. This article reviews the recently developed animal transgenic technologies, including the germ line stem cell-mediated method to improve efficiency, gene targeting to improve accuracy, RNA interference- mediated gene silencing technology, zinc-finger nuclease gene targeting technology and induced pluripotent stem cell technology. These new transgenic techniques can provide a better platform to develop transgenic animals for breeding new animal varieties and promote the development of medical sciences, livestock production, and other fields.

分类号： Q7

  • 相关文献

[1]Gene knockdown by intro-thoracic injection of double-stranded RNA in the brown planthopper, Nilaparvata lugens. Ding, Zhiping,Liu, Zewen,Liu, Shuhua,Yang, Baojun,Zhang, Chengwei.

[2]Melatonin improves reprogramming efficiency and proliferation of bovine-induced pluripotent stem cells. Bai, Chunyu,Li, Xiangchen,Gao, Yuhua,Yuan, Ziao,Hu, Pengfei,Wang, Hui,Liu, Changqing,Guan, Weijun,Ma, Yuehui,Gao, Yuhua,Yuan, Ziao,Hu, Pengfei,Wang, Hui,Liu, Changqing. 2016

[3]Construction of recombinant proteins for reprogramming of endangered Luxi cattle fibroblast cells. Hu, P. F.,Guan, W. J.,Li, X. C.,Ma, Y. H..

[4]Murine pluripotent stem cells that escape differentiation inside teratomas maintain pluripotency. Pei, Yangli,Pei, Yangli,Yue, Liang,Zhang, Wei,Xiang, Jinzhu,Han, Jianyong,Ma, Zhu. 2018

[5]Barriers for Deriving Transgene-Free Pig iPS Cells with Episomal Vectors. Du, Xuguang,Feng, Tao,Yu, Dawei,Zou, Huiying,Ma, Shuangyu,Hu, Xiaoxiang,Li, Ning,Wu, Sen,Wu, Yuanyuan,Feng, Chong,Pan, Dengke,Huang, Yongye,Ouyang, Hongsheng.

[6]Proteomic Analysis of Mouse Oocytes Identifies PRMT7 as a Reprogramming Factor that Replaces SOX2 in the Induction of Pluripotent Stem Cells. Wang, Bingyuan,Pfeiffer, Martin J.,Boiani, Michele,Drexler, Hannes C. A.,Fuellen, Georg.

[7]Gene targeting using the Agrobacterium tumefaciens-mediated CRISPR-Cas system in rice. Xu, Rongfang,Li, Hao,Qin, Ruiying,Wang, Lu,Li, Li,Wei, Pengcheng,Yang, Jianbo,Li, Hao,Wei, Pengcheng,Xu, Rongfang,Li, Li. 2014

[8]Generation of a Floxed Allele of the Mouse MicroRNA-200 Clusters. Ren, Hongyan,Bi, Yanzhen,Zheng, Xinmin,Tao, Cong,Li, Kui.

[9]Expression of hGM-CSF in silk glands of transgenic silkworms using gene targeting vector. Xue, Renyu,Cao, Guangli,Gong, Chengliang,Xue, Renyu,Chen, Huimei,Cui, Linlin,Cao, Guangli,Zheng, Xiaojian,Gong, Chengliang,Zhou, Wenlin. 2012

[10]Development of a positive-negative selection procedure for gene targeting in fish cells. Chen, SL,Hong, YH,Schartl, M.

[11]PHYSIOLOGICAL AND BIOCHEMICAL PROPERTIES ANALYSIS OF LATE-BOLTING TRANSGENIC CHINESE CABBAGE (BRASSICA RAPA L. SSP PEKINENSIS). Xia, G.,He, Q.,Zhao, S.. 2015

[12]Production of transgenic rice new germplasm with strong resistance against two isolations of Rice stripe virus by RNA interference. Ma, Jin,Song, Yunzhi,Wu, Bin,Li, Kaidong,Zhu, Changxiang,Wen, Fujiang,Jiang, Mingsong. 2011

[13]Production of marker-free and RSV-resistant transgenic rice using a twin T-DNA system and RNAi. Jiang, Yayuan,Sun, Lin,Li, Kaidong,Song, Yunzhi,Zhu, Changxiang,Jiang, Mingsong.

[14]Influence of cellulase gene knockdown by dsRNA interference on the development and reproduction of the pine wood nematode, Bursaphelenchus xylophilus. Dai, Su-Ming,Xiao, Luo,Xie, Bing-Yan,Cheng, Xin-Yue. 2010

[15]Identification of Hop stunt viroid infecting Citrus limon in China using small RNAs deep sequencing approach. Fu, Shuai,Qian, Yajuan,Xu, Yi,Zhou, Xueping,Zhou, Xueping. 2015

[16]Peptidoglycan Recognition Protein S2 From Silkworm Integument: Characterization, Microbe-Induced Expression, and Involvement in the Immune-Deficiency Pathway. Yang, Jie,Wang, Xiaonan,Wu, Jinmei,Tang, Shunming,Shen, Zhongyuan,Wu, Jinmei. 2015

[17]RNA interference of E75 nuclear receptor gene suppresses transmission of rice stripe virus in Laodelphax striatellus. Fang, Ying,Lee, Seok Hee,Kim, Jong Hoon,Park, Dong Hwan,Park, Min Gu,Woo, Ra Mi,Lee, Bo Ram,Kim, Woo Jin,Je, Yeon Ho,Choi, Jae Young,Je, Yeon Ho,Li, Shuo. 2017

[18]Involvement of a putative allatostatin in regulation of juvenile hormone titer and the larval development in Leptinotarsa decemlineata (Say). Meng, Qing-Wei,Liu, Xin-Ping,Lu, Feng-Gong,Fu, Kai-Yun,Li, Guo-Qing,Guo, Wen-Chao. 2015

[19]RNA interference of chitin synthase genes inhibits chitin biosynthesis and affects larval performance in Leptinotarsa decemlineata (Say). Shi, Ji-Feng,Mu, Li-Li,Chen, Xu,Li, Guo-Qing,Guo, Wen-Chao. 2016

[20]Effective inhibition of Japanese encephalitis virus replication by small interfering RNAs targeting the NS5 gene. Qi, Wen-Bao,Hua, Rong-Hong,Yan, Li-Ping,Tong, Guang-Zhi,Wu, Dong-Lai,Qi, Wen-Bao,Tong, Guang-Zhi,Zhang, Gui-Hong,Ren, Tao,Liao, Ming. 2008

作者其他论文 更多>>

微信小程序