Rapidly evolving R genes in diverse grass species confer resistance to rice blast disease

文献类型： 外文期刊

第一作者： Yang, Sihai

作者： Yang, Sihai;Li, Jing;Zhang, Xiaohui;Huang, Ju;Chen, Jian-Qun;Tian, Dacheng;Zhang, Qijun;Hartl, Daniel L.

作者机构：

关键词： genes;grass;species

期刊名称：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA （ 影响因子：11.205； 五年影响因子：12.291 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： We show that the genomes of maize, sorghum, and brachypodium contain genes that, when transformed into rice, confer resistance to rice blast disease. The genes are resistance genes (R genes) that encode proteins with nucleotide-binding site (NBS) and leucine-rich repeat (LRR) domains (NBS-LRR proteins). By using criteria associated with rapid molecular evolution, we identified three rapidly evolving R-gene families in these species as well as in rice, and transformed a randomly chosen subset of these genes into rice strains known to be sensitive to rice blast disease caused by the fungus Magnaporthe oryzae. The transformed strains were then tested for sensitivity or resistance to 12 diverse strains of M. oryzae. A total of 15 functional blast R genes were identified among 60 NBS-LRR genes cloned from maize, sorghum, and brachypodium; and 13 blast R genes were obtained from 20 NBS-LRR paralogs in rice. These results show that abundant blast R genes occur not only within species but also among species, and that the R genes in the same rapidly evolving gene family can exhibit an effector response that confers resistance to rapidly evolving fungal pathogens. Neither conventional evolutionary conservation nor conventional evolutionary convergence supplies a satisfactory explanation of our findings. We suggest a unique mechanism termed "constrained divergence," in which R genes and pathogen effectors can follow only limited evolutionary pathways to increase fitness. Our results open avenues for R-gene identification that will help to elucidate R-gene vs. effector mechanisms and may yield new sources of durable pathogen resistance.

分类号： N

  • 相关文献

[1]Application of near-infrared reflectance spectroscopy in grass breeding with space flight mutagenesis. Ren Wei-bo,Han Jian-guo,Yun-wei, Zhang,Hui-qin, Guo,Ren Wei-bo. 2008

[2]The application of near-infrared reflectance spectroscopy in seeds quality certification. Ren Wei-bo,Han Jian-guo,Zhang Yun-wei,Ren Wei-bo,Guo Hui-qin. 2008

[3]Rapid genome evolution revealed by comparative sequence analysis of orthologous regions from four triticeae genomes. Gu, YQ,Coleman-Derr, D,Kong, XY,Anderson, OD.

[4]HIGH LEVELS OF ERGONOVINE AND LYSERGIC ACID AMIDE IN TOXIC ACHNATHERUM INEBRIANS ACCOMPANY INFECTION BY AN ACREMONIUM-LIKE ENDOPHYTIC FUNGUS. Miles, CO,Lane, GA,diMenna, ME,Garthwaite, I,Piper, EL,Ball, OJP,Latch, GCM,Allen, JM,Hunt, MB,Bush, LP,Min, FK,Fletcher, I,Harris, PS.

[5]Factors influencing the distribution of lactic acid bacteria on Pennisetum grasses. Chen, Xinzhu,Dong, Zhaoxia,Zhang, Jianguo,Chen, Xinzhu,Zhuang, Yifen.

[6]Comparative Study of Phenolic Compounds and Antioxidant Activity in Different Species of Cherries. Liu, Yun,Zhong, Fei,Tian, Rongrong,Li, Tianhong,Liu, Xinyan,Zhang, Kaichun,Zhang, Xiaoming. 2011

[7]Identification and Genetic Division of Fusarium graminearum and Fusarium asiaticum by Species-Specific SCAR Markers. Zhang, Xu,Ma, Hong-xiang,Zhou, Yong-jin,Xing, Jin-cheng,Chen, Jian-hua,Yu, Gui-hong,Sun, Xiao-bo,Wang, Lei,Zhou, Yong-jin. 2014

[8]Western honeybee drones and workers (Apis mellifera ligustica) have different olfactory mechanisms than eastern honeybees (Apis cerana cerana). Woltedji, Dereje,Song, Feifei,Zhang, Lan,Gala, Alemayehu,Han, Bin,Feng, Mao,Fang, Yu,Li, Jianke.

[9]Refining a biotic ligand model for nickel toxicity to barley root elongation in solution culture. Li, Bo,Ma, Yibing,Zhang, Xuan,Wang, Xuedong,Zhang, Xuan,Wang, Xuedong.

[10]Proteomic analysis of cow, yak, buffalo, goat and camel milk whey proteins: Quantitative differential expression patterns. Yang, Yongxin,Bu, Dengpan,Zhao, Xiaowei,Sun, Peng,Wang, Jiaqi,Zhou, Lingyun,Yang, Yongxin,Zhao, Xiaowei.

[11]Responses of pepper to waterlogging stress. Dai, X. Z.,Zhang, Z. Q.,Zou, X. X.,Ou, L. J.,Ou, L. J.. 2011

[12]Prevalence of Coccidiosis in Domestic Rabbits (Oryctolagus cuniculus) in Northwest China. Qiao, J.,Meng, Q. L.,Chen, C. F.,Wang, J. W.,Wang, W. S.,Zhang, Z. C.,Cai, K. J.,Yang, L. H.,Qiao, J.,Cai, X. P.,Tian, G. F.. 2012

[13]Rumen ciliated protozoan fauna of the yak (Bos grunniens) in China with the description of Entodinium monuo n. sp.. Guirong,Su, NR,Hua, ZX,Zhu, S,Imai, SC.

[14]Arsenic Distribution, Species, and Its Effect on Maize Growth Treated with Arsenate. Ci Xiao-ke,Liu Hua-lin,Hao Yu-bo,Zhang Ji-wang,Liu Peng,Dong Shu-ting,Liu Hua-lin,Ci Xiao-ke. 2012

[15]Genetic Variation and Population Structure of the White Rhinoceros. Hou, Guanyu,Zeng, Hongpu,Wang, Dongjin,Zhou, Hanlin. 2012

[16]Effects of Different Fertilizers with Material Properties on Hot Pepper Growth and Microorganisms. Yang, Guang,Zhang, Qing,Gong, Na,Ma, Yue. 2013

[17]Succession of bacterial communities during composting process as detected by 16S rRNA clone libraries analysis. Tian, Wei,Sun, Qian,Zhang, Zhenhua,Chen, Da,Li, Chunyu,Shen, Qirong,Shen, Biao,Tian, Wei,Zhang, Zhenhua,Xu, Dabing.

[18]Development and Application of Genic Simple Sequence Repeat Markers from the Transcriptome of Loquat. Li, Xiaoying,Xu, Hongxia,Chen, Junwei,Feng, Jianjun.

[19]Effect of GCSC-BtA biocide on abundance and diversity of some cabbage pests as well as their natural enemies in southeastern China. Sengonca, C,Liu, B.

[20]Identification of Splice Variants, Targeted MicroRNAs and Functional Single Nucleotide Polymorphisms of the BOLA-DQA2 Gene in Dairy Cattle. Hou, Qinlei,Huang, Jinming,Ju, Zhihua,Li, Qiuling,Li, Liming,Wang, Changfa,Sun, Tao,Wang, Lingling,Hou, Minghai,Zhong, Jifeng,Hang, Suqin.

作者其他论文 更多>>

微信小程序