文献类型: 外文期刊
第一作者: Wang, Xiu-Ran
作者: Wang, Xiu-Ran;Yan, Guang-Mou;Zhang, Rui;Wang, Xing-Long;Wang, Xiu-Ran;Zhang, Rui;Lang, Xu-Long;Li, Xiao-Yan;Chen, Si;Qian, Jing;Wang, Xing-Long;Wang, Xiu-Ran;Qian, Jing;Yang, Yan-Ling
作者机构:
关键词: ABC transporter;Brucellosis;Cytokine;ELISA;Rough mutant
期刊名称:MOLECULAR MEDICINE REPORTS ( 影响因子:2.952; 五年影响因子:2.754 )
ISSN:
年卷期:
页码:
收录情况: SCI
摘要: Brucellosis is an infectious disease affecting humans and animals worldwide. Effective methods of control include inducing immunity in animals by vaccination and elimination. Brucella abortus S19 is one of the popular vaccines for control of cattle brucellosis, as it has low virulence. In this paper, allelic exchange plasmids of wzm and wzt genes were constructed and partially knocked out to evaluate the effects on the induction of immunity to Brucella abortus S19 mutants. Cytokine secretion in vitro, INF-γ induction in vivo and antibody dynamics were evaluated. These data suggested that the immunity-eliciting ability of the wzm and wzt gene deletion mutants was similar, although reduced compared with the S19 strain. The results demonstrated that the wzt gene may be more important in the regulation of the induction of immunity than the wzm gene.
分类号: R3
- 相关文献
作者其他论文 更多>>
-
Effect of environmental factors on the control of milky disease in Chinese mitten crab (Eriocheir sinensis)
作者:Zhang, Rui;Zhao, Zhigang;Guo, Kun;Wang, Shihui;Luo, Liang;Zhang, Rui;Zhao, Zhigang;Guo, Kun;Wang, Shihui;Luo, Liang;Zhao, Xu;Deng, Xiangyi
关键词:Eriocheir sinensis; Metschnikowia bicuspidata; disease control; microbial flora; temperature; alkali pH
-
Comprehensive analysis of the transcriptome-wide m6A Methylome in sheep testicular development
作者:Xi, Binpeng;Lu, Zengkui;Zhang, Rui;Li, Jianye;An, Xuejiao;Yue, Yaojing;Xi, Binpeng;Lu, Zengkui;Zhang, Rui;Li, Jianye;An, Xuejiao;Yue, Yaojing;Xi, Binpeng;Zhao, Shengguo
关键词:mRNA m6A methylation; Testicular development; F1 hybrid of Southdown x Hu sheep; Spermatogenesis
-
Multi-omics revealed the mechanisms of AgNP-priming enhanced rice salinity tolerance
作者:Chen, Si;Zhao, Lijuan;Pan, Zhengyan;Peralta-Videa, Jose R.
关键词:
-
Responsive root traits and mitigating strategies for wheat production under single or combined abiotic stress
作者:Chen, Si;Long, Lizhi;Sun, Xiaolei;Parsons, David;Zhou, Zhenjiang
关键词:Root traits; Multiple abiotic stress; Root plasticity; Wheat production; Agronomic practices
-
Long Noncoding RNA-Messenger RNA (lncRNA-mRNA) Network in Resistance to Gummy Stem Blight (Stagonosporopsis cucurbitacearum) of Melon Plant Introduction (PI) 420145
作者:Zhang, Rui;Chen, Jing;Lu, Xiumei;Cheng, Chunyan;Li, Ji;Lou, Qunfeng;Wang, Yuhui;Qian, Chuntao;Zhang, Yongbing
关键词:melon; gummy stem blight; microscopic structure; mRNA; lncRNA
-
Assessment of the bioflocculant production and safety properties of Metabacillus hrfriensis sp. nov. based on phenotypic and whole-genome sequencing analysis
作者:Zhang, Rui;Zhao, Zhigang;Luo, Liang;Wang, Shihui;Guo, Kun;Xu, Wei;Zhang, Rui;Zhao, Zhigang;Luo, Liang;Wang, Shihui;Guo, Kun;Xu, Wei
关键词:Bioflocculants; EPS; Bioflocculant-production bacteria; Safety assessment; Metabacillus
-
Integration of digital phenotyping, GWAS, and transcriptomic analysis revealed a key gene for bud size in tea plant (Camellia sinensis)
作者:Zhang, Shuran;Chen, Si;Fu, Zhilu;Li, Fang;Chen, Qiyu;Ma, Jianqiang;Chen, Liang;Chen, Jiedan;Chen, Yuanquan
关键词: