A new aromatic amine from fungus Pestalotiopsis vaccinii

文献类型： 外文期刊

第一作者： Zhou, Xuefeng

作者： Zhou, Xuefeng;Lin, Xiuping;Ma, Wanlei;Chen, Zhefang;Yang, Bin;Liu, Yonghong;Fang, Wei

作者机构：

关键词： Pestalotiopsis vaccinii;Pestalamine A;Cytotoxicity

期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： A new aromatic amine named pestalamine A (1), as well as a known diketopiperazine (2) and four known phenol or aromatic amine derivatives (3-6) were isolated from mangrove-derived endophytic fungus Pestalotiopsis vaccinii. The structure of pestalamine A (1) was determined by spectroscopic methods, especially 2D NMR analyses. Pestalamine A (1) showed moderate cytotoxicities against MCF-7, HeLa, and HepG2 human cancer cell lines with IC50 values of 40.3, 22.0, and 32.8 mu M, respectively.

分类号： Q946

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