FLUORIDE-INDUCED OXIDATIVE DAMAGE AND DNA-PROTEIN CROSSLINKS IN TM3 MOUSE LEYDIG CELLS

文献类型： 外文期刊

第一作者： Yang, Zijun

作者： Yang, Zijun;Song, Chao;Zhang, Feifei;Zhao, Hongxian;Du, Boqiang;Cao, Xiaodan

作者机构：

关键词： Antioxidant enzymes;DNA-protein crosslinks;Fluoride-induced cell damage;Lipid peroxidation;Oxidation hyperirritability;TM3 mouse Leydig cells

期刊名称：FLUORIDE （ 影响因子：1.224； 五年影响因子：1.368 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： This in vitro study was conducted to evaluate the effect of fluoride (F) on oxidative damage and DNA-protein crosslinks (DPCs) in TM3 mouse Leydig cells. Sodium fluoride at concentrations of 0, 200, 400, 600, and 800 μmol/L was administered to TM3 mouse Leydig cells for 24 hr. The activities of the antioxidant enzymes glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and catalase (CAT), along with the contents of glutathione (GSH) and malondialdehyde (MDA), plus the levels of DPCs were determined. The results showed that F administration significantly altered the levels of all of these factors compared to those of the control. The activities of antioxidant enzymes and GSH contents showed a dose-dependent decrease, the levels of lipid peroxidation and DPCs showed a dose-dependent increase. Combining all the data, the results suggest that F induces the oxidation hyperirritability in cultures of TM3 mouse Leydig cells, resulting in DPCs.

分类号： O61

  • 相关文献

[1]Physiological response of Monimopetalum chinense to light stress under habitat fragmentation. Zhang, X. P.,Hao, C. Y.,Fan, R.,Wu, H. S.,Zhang, X. P.,Wang, L.,Chen, W. L.,Zhang, X. P.,Wang, L.,Chen, W. L.,Chen, Z. L.. 2010

[2]Changes by cadmium stress in lipid peroxidation and activities of lipoxygenase and antioxidant enzymes in Arabidopsis are associated with extracellular ATP. Hou, Qin-zheng,Jia, Ling-yun,Liang, Jun-yu,Feng, Han-qing,Wen, Jing,Shi, Dai-long,Wang, Qing-wen,Ye, Guang-ji,Wang, Rong-fang. 2017

[3]FLUORIDE-INDUCED CELL CYCLE ARREST, APOPTOSIS, AND DNA DAMAGE IN TM3 MOUSE LEYDIG CELLS. Song, Chao,Yang, Zijun,Guo, Shuzhou,Shang, Zesong,Cao, Xiaodan.

[4]Supplementation of xanthophylls increased antioxidant capacity and decreased lipid peroxidation in hens and chicks. Gao, Yu-Yun,Xie, Qing-Mei,Ma, Jing-Yun,Zhang, Xiang-Bin,Zhu, Ji-Mei,Sun, Bao-Li,Jin, Ling,Bi, Ying-Zuo,Shu, Ding-Ming,Bi, Ying-Zuo. 2013

[5]Heme Oxygenase-1 is Associated with Wheat Salinity Acclimation by Modulating Reactive Oxygen Species Homeostasis. Xie, Yanjie,Cui, Weiti,Shen, Wenbiao,Yang, Qing,Xie, Yanjie,Cui, Weiti,Shen, Wenbiao,Yang, Qing,Yuan, Xingxing. 2011

[6]Silicon-enhanced resistance to rice blast is attributed to silicon-mediated defence resistance and its role as physical barrier. Sun, Wanchun,Zhang, Jie,Fan, Qionghua,Xue, Gaofeng,Li, Zhaojun,Liang, Yongchao,Sun, Wanchun.

[7]Silicon ameliorates manganese toxicity by regulating manganese transport and antioxidant reactions in rice (Oryza sativa L.). Li, Ping,Song, Alin,Li, Zhaojun,Fan, Fenliang,Liang, Yongchao,Li, Ping.

[8]Effect of ultraviolet-B irradiation on lipid peroxidation in spinach leaves. Huang, SB,Liu, XZ,Dai, QJ,Wang, ZX. 1998

[9]Effects of chestnut tannins on carcass characteristics, meat quality, lipid oxidation and fatty acid composition of rabbits. Gai, Francesco,Gasco, Laura,Brugiapaglia, Alberto,Lussiana, Carola,Zoccarato, Lvo,Liu, Hua Wei,Tong, Jian Ming,Guo, Kai Jun.

[10]The alleviation of zinc toxicity by silicon is related to zinc transport and antioxidative reactions in rice. Song, Alin,Li, Ping,Li, Zhaojun,Fan, Fenliang,Liang, Yongchao,Nikolic, Miroslav.

[11]In vitro antioxidative activities of three marine oligosaccharides. Wang, Peng,Jiang, Xiaolu,Jiang, Yanhua,Hu, Xiaoke,Mou, Haijin,Li, Man,Guan, Huashi. 2007

[12]Overexpression of Arabidopsis CBF1 gene in transgenic tobacco alleviates photoinhibition of PSII and PSI during chilling stress under low irradiance. Yang, Jia-Sen,Meng, Jing-Jing,Bi, Yu-Ping,Xu, Ping-Li,Guo, Feng,He, Qi-Wei,Li, Xin-Guo,Yang, Jia-Sen,Meng, Jing-Jing,Bi, Yu-Ping,Xu, Ping-Li,Guo, Feng,Wan, Shu-Bo,Li, Xin-Guo,Wang, Ran,Wang, Ran.

[13]Low-current & high-frequency electrical stunning increased oxidative stress, lipid peroxidation, and gene transcription of the mitogen-activated protein kinase/nuclear factor-erythroid 2-related factor 2/antioxidant responsive element (MAPK/Nrf2/ARE) signaling pathway in breast muscle of broilers. Xu, Lei,Zhang, Hai-jun,Yue, Hong-yuan,Wu, Shu-geng,Qi, Guang-hai,Xu, Lei,Yang, Hai-ming,Wang, Zhi-yue. 2018

[14]Effect of arbuscular mycorrhizal fungi on growth, mineral nutrition, antioxidant enzymes activity and fruit yield of tomato grown under salinity stress. Latef, Arafat Abdel Hamed Abdel,He Chaoxing.

[15]Effects of Different Copper Sources and Levels on Plasma Superoxide Dismutase, Lipid Peroxidation, and Copper Status of Lambs. Cheng, Jianbo,Fan, Caiyun,Zhang, Zijun,Wang, Lisheng,Ma, Hui,Jia, Zhihai,Zhu, Xiaoping. 2011

[16]Effects of acute heat stress and subsequent stress removal on function of hepatic mitochondrial respiration, ROS production and lipid peroxidation in broiler chickens. Tan, Gao-Yi,Fu, Yu-Qiang,Feng, Jin-Hai,Zhang, Min-Hong,Yang, Lin,Tan, Gao-Yi,Fu, Yu-Qiang. 2010

[17]Alleviation of Chromium Toxicity by Silicon Addition in Rice Plants. Zeng Fan-rong,Qiu Bo-yin,Wu Fei-bo,Zhang Guo-ping,Zhao Fu-sheng,Ouyang You-nan. 2011

[18]Effect of genistein on antioxidative defence system and membrane fluidity in chick skeletal muscle cells. Jiang, Z. Y.,Jiang, S. Q.,Lin, Y. C.,Ma, X. Y.,Xi, P. B.,Cao, T.,Wang, X. Q.. 2008

[19]The inhibiting activity of areca inflorescence extracts on human low density lipoprotein oxidation induced by cupric ion. Chen, Weijun,Zhang, Chunmei,Huang, Yulin,Cheng, Fangfang,Shen, Yan,Tang, Minmin,Zheng, Yajun,Zhao, Songlin,Chen, Weijun,Wang, Rencai,Zhang, Chunmei,Zhao, Songlin. 2012

[20]Response of oxidative stress defense systems in rice (Oryza sativa) leaves with supplemental UV-B radiation. Dai, QJ,Yan, B,Huang, SB,Liu, XZ,Peng, SB,Miranda, MLL,Chavez, AQ,Vergara, BS,Olszyk, DM. 1997

作者其他论文 更多>>

微信小程序