Utilization of Chitosan-Lactide Copolymer Nanoparticles as Controlled Release Pesticide Carrier for Pyraclostrobin Against Colletotrichum gossypii Southw

文献类型： 外文期刊

第一作者： Huang, Qi-Liang

作者： Huang, Qi-Liang;Xu, Lei;Cao, Li-Dong;Li, Feng-Min;Wang, Xiang-Jing

作者机构：

关键词： Chitosan;fungicidal activity;nanoparticles;pyraclostrobin;sustained release

期刊名称：JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY （ 影响因子：2.262； 五年影响因子：2.064 ）

ISSN：

年卷期：

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收录情况： SCI

摘要： Low effective availability of modern pesticides places heavy burdens on both the environment and costs to farmers. Nano-augmented delivery systems seem to be more promising to address the present challenge modern pesticides are facing. In this article, biodegradable chitosan-lactide copolymer (CPLA) was prepared and characterized as hydrophobic pesticide-pyraclostrobin carrier. Nano-precipitation method was used to fabricate pyraclostrobin-loaded nanoparticles. Loading content (LC), encapsulation efficiency (EE), size, and size distribution of the resulting nanoparticles were investigated. The size of pesticide-loaded nanoparticles can be adjusted between 77 to 128 nm by varying the feed mass ratio of copolymer to pyraclostrobin from 50/1 to 5/1. Compounds contained within nanoparticles was protected from light compared with the technical material. The pyraclostrobin-loaded nanoparticles showed an initial burst, subsequent sustained and pH-controlled release profile. Compared to 25% pyraclostrobin emulsifiable concentrate (EC), the nanoparticles demonstrated better fungicidal activity against Colletotrichum gossypii Southw under long incubation time, which further exhibited sustained release characteristic.

分类号： O648

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