Carbazole alkaloids from the peels of Clausena lansium

文献类型: 外文期刊

第一作者: Deng, Hui-Dong

作者: Deng, Hui-Dong;Mei, Wen-Li;Wang, Hui;Guo, Zhi-Kai;Dong, Wen-Hua;Wang, Hao;Dai, Hao-Fu;Deng, Hui-Dong;Li, Shao-Peng

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期刊名称:JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH ( 影响因子:1.569; 五年影响因子:1.598 )

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收录情况: SCI

摘要: A new carbazole alkaloid, claulansine K (1), together with six known carbazole alkaloids (2-7), was isolated from the peels of Clausena lansium (Lour.) Skeels. The new compound was elucidated using a combination of ID and 2D NMR (HMQC, HMBC, COSY, and ROESY) techniques, and HR-EI-MS analyses. Compound 1 showed in vitro alpha-glucosidase inhibitory activity with the IC50 value of 0.11 mM. Compound 2 exhibited moderate antibacterial activity against Staphylococcus aureus with the diameter of inhibition zone of 14.2 mm.

分类号: R9

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