MicroRNAs in Autoimmune Diseases

文献类型: 外文期刊

第一作者: Qu, Zigang

作者: Qu, Zigang;Li, Wenhui;Fu, Baoquan

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期刊名称:BIOMED RESEARCH INTERNATIONAL ( 影响因子:3.411; 五年影响因子:3.62 )

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收录情况: SCI

摘要: Autoimmune diseases (ADs) are featured by body's immune responses being directed towards its own specific target organs or multiple organ systems, causing persistent inflammation and consequent tissue damage. miRNAs are small noncoding RNAs in a size of approximately 22 nt that play important regulatory roles in many organisms by cleavage or translational inhibition of targeted mRNAs. Many miRNAs are reported to be differentially expressed in ADs and may play a pivotal role in regulating immune responses and autoimmunity. In this review, current research progress in the miRNAs in ADs was elucidated.

分类号: R3

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