Chemiluminescence diminishment on a paper-based analytical device: high throughput determination of beta-agonists in swine hair

文献类型： 外文期刊

第一作者： Chen, Xu

作者： Chen, Xu;Shi, Bo;Chen, Xu;Luo, Yong;Gao, Zhigang;Zhao, Weijie;Lin, Bingcheng;Chen, Xu;Luo, Yong;Gao, Zhigang;Zhao, Weijie;Lin, Bingcheng;Liu, Xianming;Lin, Bingcheng;Du, Yuguang

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期刊名称：ANALYTICAL METHODS （ 影响因子：2.896； 五年影响因子：2.716 ）

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收录情况： SCI

摘要： beta-Agonists are a group of illegal but widely used feed additives in the stockbreeding industry. In order to achieve simple-to-use, fast and high-throughput testing of this banned chemical, herein we suggest a paper-based analytical device on which a chemiluminescence diminishment method was performed. In this approach, extracts from swine hair samples as well as luminescent reagents, such as luminol and potassium periodate solution, in a low volume were applied to our device. It was found that the light emission was diminished by the beta-agonists extracted from the swine hair samples. The degree of diminishment is proportional to the concentration of the beta-agonists from 1.0 x 10(-5) to 1.0 x 10(-8) mol L-1. Also, the concentrations of solutions for chemiluminescence were optimized. The mechanism and reaction kinetics of chemiluminescence were discussed as well. The detection limit was obtained as 1.0 x 10(-9) mol L-1, and recoveries from 96% to 110% were achieved, both of which suggested that our method will be favourable in field applications for swine hair samples.

分类号： O65

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