A new diterpene from the fungal mycelia of Hericium erinaceus

文献类型： 外文期刊

第一作者： Zhang, Zhong

作者： Zhang, Zhong;Tang, Qing-Jiu;Zhang, Jing-Song;Yang, Yan;Shang, Xiao-Dong;Liu, Rui-Na

作者机构：

关键词： Diterpene;Hericium erinaceus;Cytotoxicity;Antibacterial activity

期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）

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年卷期：

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收录情况： SCI

摘要： One new diterpene (1) and new compound (2), along with four known compounds (3-6) were isolated from the fungal mycelia of Hericium erinaceus by the tracking method of antibacterial activity. The structures of compounds (1-6) were elucidated on the basis of spectral data. Compound (3) showed strong antibacterial activity against Helicobacter pylori (ATCC43504) and compounds (1), (2) and (4) showed moderate antibacterial activity. Compound (1) exhibited good cytotoxicity against three human cancer cell lines (K562, LANCAP, HEP2). (C) 2014 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.

分类号： Q946

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