The first lack of evidence of H7N9 avian influenza virus infections among pigs in Eastern China

文献类型： 外文期刊

第一作者： Zhao, Fu-Rong

作者： Zhao, Fu-Rong;Zhou, Dong-Hui;Lin, Tong;Shao, Jun-Jun;Wei, Ping;Zhang, Yong-Guang;Chang, Hui-Yun;Wei, Ping

作者机构：

关键词： Seroprevalence;Avian influenza virus;Swine serum;HA-ELISA

期刊名称：MICROBIAL PATHOGENESIS （ 影响因子：3.738； 五年影响因子：3.663 ）

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收录情况： SCI

摘要： In this study, we sought to examine whether evidence existed suggesting that pigs were being infected with the novel H7N9 avian influenza virus. From November 2012 to November 2013, blood was drawn from 1560 pigs from 100 large farms in 4 provinces of eastern China. Many of these pigs were in close proximity to wild birds or poultry. Swine sera were studied using hemagglutinin inhibition (HI) assays and enzyme-linked immunosorbent assays (ELISAs) against the H7 antigen derived from the emergent H7N9 avian influenza virus (AIV). Only 29 of the 1560 samples had HI titers of 1:20 when using the H7N9 AIV antigens, and none of the 29 (H7N9 AIV) HI-positive samples were positive when using ELISA, indicating that no samples were positive for H7N9. The negative results were also verified using a novel competitive HA-ELISA. As pigs have been shown to be infected with other avian influenza viruses and as the prevalence of novel influenza A viruses (e.g., H7N9 AIV) may be increasing among poultry in China, similar seroepidemiological studies of pigs should be periodically conducted in the future. (C) 2015 Elsevier Ltd. All rights reserved.

分类号： R3

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