PcG and trxG in plants - friends or foes

文献类型： 外文期刊

第一作者： Pu, Li

作者： Pu, Li;Sung, Zinmay Renee;Pu, Li

作者机构：

关键词： Polycomb and trithorax group proteins;antagonism and cooperation;seed and floral repression;histone methylation

期刊名称：TRENDS IN GENETICS （ 影响因子：11.639； 五年影响因子：12.811 ）

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收录情况： SCI

摘要： The highly-conserved Polycomb group (PcG) and trithorax group (trxG) proteins play major roles in regulating gene expression and maintaining developmental states in many organisms. However, neither the recruitment of Polycomb repressive complexes (PRC) nor the mechanisms of PcG and trxG-mediated gene silencing and activation are well understood. Recent progress in Arabidopsis research challenges the dominant model of PRC2-dependent recruitment of PRC1 to target genes. Moreover, evidence indicates that diverse forms of PRC1, with shared components, are a common theme in plants and mammals.. Although trxG is known to. antagonize PcG, emerging data reveal that trxG can also repress gene expression, acting cooperatively with PcG. We discuss these recent findings and highlight the employment of diverse epigenetic mechanisms during development in plants and animals.

分类号： Q3

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