New insights into pri-miRNA processing and accumulation in plants

文献类型： 外文期刊

第一作者： Zhang, Shuxin

作者： Zhang, Shuxin;Yu, Bin;Zhang, Shuxin;Yu, Bin;Zhang, Shuxin;Liu, Yuhui;Liu, Yuhui

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期刊名称：WILEY INTERDISCIPLINARY REVIEWS-RNA （ 影响因子：9.957； 五年影响因子：8.247 ）

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收录情况： SCI

摘要： MicroRNAs (miRNAs) regulate many biological processes such as development, metabolism, and others. They are processed from their primary transcripts called primary miRNA transcripts (pri-miRNAs) by the processor complex containing the RNAse III enzyme, DICER-LIKE1 (DCL1), in plants. Consequently, miRNA biogenesis is controlled through altering pri-miRNA accumulation and processing, which is crucial for plant development and adaptation to environmental changes. Plant pri-miRNAs are transcribed by DNA-dependent RNA polymerase II (Pol II) and their levels are determined through transcription and degradation, whereas pri-miRNA processing is affected by its structure, splicing, alternative splicing, loading to the processor and the processor activity, which involve in many accessory proteins. Here, we summarize recent progresses related to pri-miRNA transcription, stability, and processing in plants. WIREs RNA 2015, 6:533-545. doi: 10.1002/wrna.1292 For further resources related to this article, please visit the .

分类号： Q7

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