Phylogenetic analysis of Newcastle disease viruses isolated from wild birds in the Poyang Lake region of China

文献类型: 外文期刊

第一作者: Fan, Shengtao

作者: Fan, Shengtao;Li, Qihan;Fan, Shengtao;Li, Qihan;Fan, Shengtao;Wang, Tiecheng;Li, Xue;Li, Yuanguo;Ma, Jinzhu;Yang, Songtao;Gao, Yuwei;Xia, Xianzhu;Gao, Xiaolong;Ying, Ying;Li, Yongcheng;Sun, Heting;Chu, Dong;Xu, Yu

作者机构:

关键词: genotype;Newcastle disease virus;phylogenetic analysis;Poyang Lake

期刊名称:JOURNAL OF VETERINARY MEDICAL SCIENCE ( 影响因子:1.267; 五年影响因子:1.348 )

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收录情况: SCI

摘要: Newcastle disease virus (NDV) causes a highly contagious viral disease in poultry and wild birds, and it can cause significant economic loss worldwide. Eight viral strains were isolated by inoculating embryonated chicken eggs from the Poyang Lake region of China with swab samples. All eight of the NDV isolates were identified as class I genotype 3 strains, but they diverged notablely from class II viruses. Further analysis revealed that all eight NDV isolates were lentogenic strains containing the (112)ERQERIL(117) motif at the F protein cleavage site. The strains were highly identical and were more species specific (chicken and waterfowl) than site specific (Nanchang and Duchang regions). The close phylogenetic proximity of these isolates indicates that viral transmission may happen between poultry and wild birds. Our study demonstrates that lentogenic class I NDVs exist in clinically healthy wild waterfowl and poultry within the Poyang Lake region. Active surveillance of these viruses to determine their evolution and origin is one of the most realistic strategies for preventing and controlling NDV outbreaks.

分类号: S85

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