Effect of retS gene on antibiotics production in Pseudomonas fluorescens FD6

文献类型： 外文期刊

第一作者： Zhang, Qingxia

作者： Zhang, Qingxia;Xiao, Qi;Xu, Jingyou;Tong, Yunhui;Chen, Xijun;Wen, Jia;Wei, Lihui

作者机构：

关键词： Pseudomonas;Antibiotics;RetS;Gac/Rsm

期刊名称：MICROBIOLOGICAL RESEARCH （ 影响因子：5.415； 五年影响因子：6.038 ）

ISSN：

年卷期：

页码：

收录情况： SCI

摘要： A hybrid sensor kinase termed RetS (regulator of exopolysaccharide and Type III secretion) controls expression of numerous genes in Pseudomonas aeruginosa. To investigate the function of RetS in P. fluorescens FD6, the retS gene was disrupted. Genetic inactivation of retS resulted in enhanced production of 2, 4-diacetylphloroglucinol, pyrrolnitrin, and pyoluteorin. The retS mutant also exhibited significant increase in ph1A-lacZ, prnA-lacZ, and pltA-lacZ transcription levels, influencing expression levels of the small regulatory RNAs RsmX and RsmZ. In the gacSretS double mutant, all the phenotypic changes caused by the retS deletion were reversed to the level of gacS single mutant. Furthermore, the retS mutation drastically elevated biofilm formation and improved the colonization ability of strain FD6 on wheat rhizospheres. Based on these results, we proposed that RetS negatively controlled the production of antibiotics through the Gac/Rsm pathway in P. fluorescens FD6. (C) 2015 Elsevier GmbH. All rights reserved.

分类号： Q

  • 相关文献

[1]Genetic Diversity of Nitrogen-Fixing and Plant Growth Promoting Pseudomonas Species Isolated from Sugarcane Rhizosphere. Singh, Rajesh K.,Singh, Pratiksha,Song, Qi-Qi,Xing, Yong-Xiu,Yang, Li-Tao,Li, Yang-Rui,Li, Yang-Rui. 2017

[2]Long-Term Rice and Green Manure Rotation Alters the Endophytic Bacterial Communities of the Rice Root. Zhang, Xiao-Xia,Gao, Ju-Sheng,Cao, Yan-Hua,Ma, Xiao-Tong,He, Ji-Zheng,Gao, Ju-Sheng.

[3]Identification of the para-nitrophenol catabolic pathway, and characterization of three enzymes involved in the hydroquinone pathway, in pseudomonas sp 1-7. Zhang, Shuangyu,Sun, Wen,Xu, Li,Zheng, Xiaomei,Chu, Xiaoyu,Tian, Jian,Wu, Ningfeng,Fan, Yunliu. 2012

[4]Bioremediation potential of glyphosate-degrading Pseudomonas spp. strains isolated from contaminated soil. Zhu, Jianyi,Liu, Shengnan,Gao, Han,Zhou, Xiaogang,Tao, Ke.

[5]The rice inoculant strain Alcaligenes faecalis A15 is a nitrogen-fixing Pseudomonas stutzeri. Vermeiren, H,Willems, A,Schoofs, G,de Mot, R,Keijers, V,Hai, WL,Vanderleyden, J. 1999

[6]Bacterial communities and volatile compounds in Doubanjiang, a Chinese traditional red pepper paste. Dong, L.,Huang, Q.,Wang, X..

[7]Role of Vfr in the regulation of antifungal compound production by Pseudomonas fluorescens FD6. Zhang, Qingxia,Ji, Yanyan,Xiao, Qi,Tong, Yunhui,Chen, Xijun,Chng, Soonie,Liu, Fengquan.

[8]Identification and genomic analysis of antifungal property of a tomato root endophyte Pseudomonas sp p21. Ma, Rongqin,Cheng, Zhiqiang,Lei, Shaonan,Li, Xin,Tian, Baoyu,Ma, Rongqin,Cheng, Zhiqiang,Lei, Shaonan,Li, Xin,Tian, Baoyu,Cao, Yi,Huang, Wei,Song, Yongkang.

[9]Dietary risk ranking for residual antibiotics in cultured aquatic products around Tai Lake, China. Song, Chao,Zhang, Cong,Qiu, Liping,Fan, Limin,Wu, Wei,Meng, Shunlong,Hu, Gengdong,Chen, Jiazhang,Song, Chao,Zhang, Cong,Qiu, Liping,Fan, Limin,Wu, Wei,Meng, Shunlong,Hu, Gengdong,Chen, Jiazhang,Song, Chao,Li, Le,Zhang, Cong,Qiu, Liping,Fan, Limin,Wu, Wei,Meng, Shunlong,Hu, Gengdong,Chen, Jiazhang,Li, Le,Liu, Ying,Mao, Aimin. 2017

[10]Yield Improvement of the Anti-MRSA Antibiotics WAP-8294A by CRISPR/dCas9 Combined with Refactoring Self-Protection Genes in Lysobacter enzymogenes OH11. Yu, Lingjun,Liu, Fengquan,Yu, Lingjun,Su, Wei,Du, Liangcheng,Fey, Paul D.. 2018

[11]A simple and economic method for simultaneous determination of 11 antibiotics in manure by solid-phase extraction and high-performance liquid chromatography. Feng, Yao,Zhang, Wenjuan,Liu, Yuanwang,Li, Zhaojun,Hu, Haiyan,Wei, Chaojun,Zhang, Wenjuan,Xue, Jianming. 2016

[12]Interactive Effects of Tetracyclines and Copper on Plant Growth and Nutrient Uptake by Eichhornia crassipes. Lu, Xin,Gao, Yan,Luo, Jia,Yan, Shaohua,Wang, Tong,Liu, Lizhu,Zhang, Zhenhua,Lu, Xin,Gao, Yan,Luo, Jia,Yan, Shaohua,Wang, Tong,Liu, Lizhu,Zhang, Zhenhua. 2016

[13]Identification of the streptothricin and tunicamycin biosynthetic gene clusters by genome mining in Streptomyces sp strain fd1-xmd. Yu, Yucong,Tang, Biao,Dai, Ruixue,Zhang, Bo,Chen, Liqiang,Zhao, Guoping,Ding, Xiaoming,Tang, Biao,Yang, Hua,Zhao, Guoping. 2018

[14]Temporal-spatial variation and partitioning prediction of antibiotics in surface water and sediments from the intertidal zones of the Yellow River Delta, China. Zhao, Shengnan,Liu, Xinhui,Liang, Baocui,Cui, Baoshan,Bai, Junhong,Cheng, Dengmiao,Liu, Guannan.

[15]LetR is a TetR family transcription factor from Lysobacter controlling antifungal antibiotic biosynthesis. Wang, Ping,Chen, Hongfu,Qian, Guoliang,Liu, Fengquan,Liu, Fengquan.

[16]Interspecific differences in growth response and tolerance to the antibiotic sulfadiazine in ten clonal wetland plants in South China. Chen, Jinfeng,Sun, Yingbo,Huang, Lili,Zhang, Peixia,Zou, Chunping,Yu, Bo,Zhu, Genfa,Zhao, Chaoyi,Xu, Huilian.

[17]Occurrence, fate, and ecotoxicity of antibiotics in agro-ecosystems. A review. Liu, Wenke,Du, Lianfeng,Liu, Wenke.

[18]Changes in antimicrobial resistance among Salmonella enterica subspecies enterica serovar Pullorum isolates in China from 1962 to 2007. Pan, Zhiming,Wang, Xiaoquan,Zhang, Xiaoming,Geng, Shizhong,Chen, Xiang,Pan, Weijuan,Cong, Qiuxia,Jiao, Xinan,Liu, Xiufan,Liu, Xuexian.

[19]Comparative proteomic analysis reveals intracellular targets for bacillomycin L to induce Rhizoctonia solani Kuhn hyphal cell death. Zhang, Bao,Qin, Yuxuan,Han, Yuzhu,Li, Pinglan,Qin, Yuxuan,Li, Pinglan,Zhang, Bao,Dong, Chunjuan,Shang, Qingmao.

[20]Antibiotic-induced male-sterility in oilseed flax. Dang, ZH,Zhang, JP,She, X. 2000

作者其他论文 更多>>

微信小程序