Genome-wide functional analysis of SSR for an edible mushroom Pleurotus ostreatus

文献类型: 外文期刊

第一作者: Qu, Jibin

作者: Qu, Jibin;Huang, Chenyang;Zhang, Jinxia

作者机构:

关键词: Simple sequence repeat;Pleurotus ostreatus genome;Functional enrichment analysis;Repeating amino acid

期刊名称:GENE ( 影响因子:3.688; 五年影响因子:3.329 )

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收录情况: SCI

摘要: Simple sequence repeats (SSRs) play specific roles in many biological activities. In this paper, we focused on SSRs in the genome of Pleuroms ostreatus, which is a widely cultivated edible mushroom. The distribution curves of SSRs and exons are opposite throughout the genome, which means that SSRs are mostly located in non-coding regions. A comparative analysis of nine fungi suggests that Agaricomycotina fungi have similar SSR distributions. Functional enrichment analysis on the SSR-containing gene set uncovers enriched functions about environmental interactions and important cellular functions for life. Trinucleotide SSRs account for an extremely high fraction of all SSRs, and in exonic regions, they are equivalent to inserting repeating amino acids (RAAs) into the protein sequences. The RAA indel could partly explain some enriched functions of the genes they modify. Agaricomycotina fungi have similar distributions of RAAs, indicating that this may be a potential common mechanism for some specific functions. (C) 2015 Elsevier B.V. All rights reserved.

分类号: R394

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