文献类型： 外文期刊
第一作者： Peng, Jun-Lin
作者： Peng, Jun-Lin;Jun-Wang;Kong, Fan-Dong;Wang, Pei;Gai, Cui-Juan;Mei, Wen-li;Dai, Hao-fu;Peng, Jun-Lin;Liu, Zi-Qi;Jiang, Bei
作者机构：
关键词： Chukrasia tabularis;Phragmalin;Limonoid;alpha-Glucosidase activity
期刊名称：PHYTOCHEMISTRY LETTERS （ 影响因子：1.679； 五年影响因子：1.861 ）
ISSN：
年卷期：
页码：
收录情况： SCI
摘要： Phytochemical investigation on the stems of Chukrasia tabularis A. Juss led to the isolation of two new phragmalin-type limonoids and three known ones. The structures of the new compounds were elucidated as Chuklarisin A (1) and Chuklarisin B (2) by spectroscopic techniques (IR, HRESIMS, 1D and 2D NMR) and comparing with published data. All the compounds were evaluated for alpha-glucosidase inhibitory activity in vitro. Compounds 2, 3, and 4 exhibited inhibitory activity against alpha-glucosidase with IC50 values of 0.96, 0.03, and 0.53 mM, respectively (acarbose as positive control, IC50 0.95 mM). (C) 2016 Phytochemical Society of Europe. Published by Elsevier B.V. All rights reserved.
分类号： Q946
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